lvaline

A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.

Fructosylvaline(Fru-val) is present in miso, white wine and sake and has been associated with oxidative browning of white wine and sake.

Acetylvaline (Ac-Val-OH) is used as an indicator of diseases such as type 2 diabetes, obesity and retinopathy.

Valylvaline acetate is a dipeptide and a PEPT1 agonist with an EC50 of 0.07mM.

Valylvaline (Val-val) is a dipeptide compound that can be used for protein synthesis.

Prolylvaline is used as a peptide with antibacterial properties.

γ-Glutamylvaline acts as an activator of the calcium-sensing receptor (CaSR) and possesses anti-inflammatory biological activity. It inhibits TNF-α-mediated proinflammatory cytokine synthesis and upregulates Wnt5a expression. By activating the CaSR signaling pathway in 3T3-L1 mouse adipocytes, it improves the chronic low-grade inflammatory state.

Isoleucylvaline is a dipeptide.

Pyroglutamylvaline is a dipeptide.

N-Lactylvaline is an endogenous metabolite detectable in patients with intermediate maple syrup urine disease.

N-Acetylvaline is a commonly used biochemical reagent that can serve as a biomaterial or organic compound for life science research.

N-Oleoyl valine is an endogenous N-acyl amine that acts as an antagonist at the transient receptor potential vanilloid type 3 (TRPV3) receptor, which is involved in thermoregulation. N-Oleoyl valine is increased in mice following cold exposure for up to at least 16 days. Acute lung injury in mice increases the concentration of N-Oleoyl valine in lung tissue. N-acyl amines also promote mitochondrial uncoupling.

N-Oleoyl Valine Ammonium salt is an N-acyl amide compound that is a TRPV3 antagonist and can be used to study inflammation.

DL-Penicillamine (3-Sulfanylvaline) is a chelating agent recommended for the removal of excess copper in patients with Wilson's disease. DL-Penicillamine is only found in individuals that have used or taken this drug. It is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease. From in vitro studies which indicate that one atom of copper combines with two molecules of DL-penicillamine. DL-Penicillamine also reduces excess cystine excretion in cystinuria. This is done, at least in part, by disulfide interchange between DL-penicillamine and cystine, resulting in the formation of penicillamine-cysteine disulfide, a substance that is much more soluble than cysteine and is excreted readily. DL-Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. The mechanism of action of DL-penicillamine in rheumatoid arthritis is unknown although it appears to suppress disease activity. Unlike cytotoxic immunosuppressants, DL-penicillamine markedly lowers IgM rheumatoid factor but produces no significant depression in absolute levels of serum immunoglobulins. Also unlike cytotoxic immunosuppressants which act on both, DL-penicillamine in vitro depresses T-cell activity but not B-cell activity.

Glycyl-L-valine, a dipeptide composed of glycine and valine, is an incomplete breakdown product of protein digestion or protein catabolism (incomplete breakdown product of protein digestion or protein catabolism).

DL-Valine (H-DL-Val-OH) is 2-amino-3-methylbutanoic acid.It is synthesized in plants via several steps starting from pyruvic acid.

Valtorcitabine is a DNA polymerase inhibitor that may be used in the treatment of HBV infection.

Jasmonoyl-valine is one of the amino acid conjugates of jasmonic acid. It can be extracted from the alpine plant Saxifraga longifolia and may play a role in regulating photoprotection or photosynthetic mechanisms.

MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a promising stance in the delivery of therapeutic agents by providing distinct advantage of improving therapeutic potential of drugs. Use of specialized linkers makes them unique in their in vivo therapeutic application by providing target tissue-specific release of drug.

N-(tert-Butoxycarbonyl)-N-methyl-L-valine is a useful organic compound for research related to life sciences. The catalog number is T65258 and the CAS number is 45170-31-8.

N-Methyl-L-valine (catalog number T65884, CAS number 2480-23-1) is a valuable organic compound for life sciences research.

(tert-Butoxycarbonyl)-L-valyl-L-valine (catalog number: T66012; CAS number: 69209-73-0) is a useful organic compound for research in life sciences.

Boc-L-valine methyl ester, with catalog number T66803 and CAS number 58561-04-9, is a valuable organic compound for research in life sciences.

N-Fmoc-glycyl-L-valine is a dipeptide protected at the N-terminus by 9-fluorenylmethoxycarbonyl (Fmoc) and can be used as a starting or extension amino acid unit in solid-phase peptide synthesis (SPPS). N-Fmoc-glycyl-L-valine is stable in organic solvent systems and is suitable for peptide synthesis and drug design research.