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Results for "
kras g12c mutant protein inhibitor a-1
" in TargetMol Product Catalog- Inhibitors & Agonists2
KRAS G12C mutant protein inhibitor A-1
T778052658538-04-4
KRAS G12C mutant protein inhibitor A-1 can be used in studies about Ras.
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sah-sos1a tfa
T76059
SAH-SOS1A TFA is a peptide-based SOS1 KRAS protein interaction inhibitor. SAH-SOS1A TFA binds to wild-type and mutant KRAS (G12D, G12V, G12C, G12S, and Q61H) with nanomolar affinity ( EC 50 =106-175 nM). SAH-SOS1A TFA directly and independently blocks nucleotide association. SAH-SOS1A TFA impairs KRAS-driven cancer cell viability and exerts its effects by on-mechanism blockade of the ERK-MAPK phosphosignaling cascade downstream of KRAS [1] .
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