immunoglobulin g-2

Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand

Human Immunoglobulin G2 (Human IgG2) is a subclass of human IgG antibodies. An IgG2 deficiency can result in a diminished antibody response to bacterial polysaccharides, potentially increasing vulnerability to infections from encapsulated bacteria.

hIgG-hFc receptor-IN-1 is a human immunoglobulin G - human neonatal Fc receptor (hIgG-hFcRn) protein-protein interaction inhibitor (IC50: 2 μM).

Anti-Mouse IFN gamma Antibody (H22) is an IFN-γ-targeting inhibitory antibody raised in Armenian hamsters against mouse IFN-γ that interferes with the specific binding of ¹²⁵I-rIFN-γ to macrophages, exerts an inhibitory effect on macrophage-activating factor (MAF) activity and IFN-γ-dependent antiviral activity with an ID₅₀ of 56 ng and 2 ng, respectively, and is also capable of neutralizing endogenous IFN-γ in mice. H22 antibody is commonly employed in research on inflammatory and infectious diseases, including the pathological mechanism investigation of arthritis.