exo 1

Exo-1 (Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate) is a synthetic compound that has been shown to affect the metabolism of various nutrients, as well as the regulation of various hormones. It has also been shown to have anti-inflammatory and anti-tumor effects.

EXO1-IN-1 (Compound F684) is a potent and selective inhibitor of exonuclease 1 (EXO1) with an IC50 of 15.7 μM. It inhibits DNA end resection, promotes the accumulation of DNA double-strand breaks, and induces S-phase polyadenylation, thereby disrupting DNA repair pathways in homologous recombination-deficient (HRD) cancer cells. This selectivity effectively targets and kills tumor cells with homologous recombination gene defects, such as BRCA1/2 mutations. EXO1-IN-1 holds promise for researching cancers with homologous recombination deficiencies, including BRCA-related tumors.

Exo1 is an inhibitor of the exocytic pathway

exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin signaling pathway.

Exo-3-amino-9-methyl-9-azabicyclo[3,3,1]nonane ,with CAS No. 76272-41-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Exo-3-amino-9-methyl-9-azabicyclo[3,3,1]nonane provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

exo-Hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione is a useful organic compound for research related to life sciences. The catalog number is T65551 and the CAS number is 14805-29-9.

exo-α-1,2-Galactosidase, Bacteroides thetaiotaomicron, is a glycoside hydrolase.

exo-α-1,2-Mannosidase, Bacteroides thetaiotaomicron (EC.3.2.1.163), is a glycoside hydrolase involved in the breakdown of mannans.

Exo-α-Galactosidase Isoenzyme from Bacteroides thetaiotaomicron (EC.3.2.1.22) is a glycoside hydrolase enzyme.

Exo-α-1,4-Mannosidase, Bacteroides thetaiotaomicron (EC.3.2.1.163), is a glycoside hydrolase involved in the degradation of mannan.

Exo-α-1,2-Fucosidase, derived from Bifidobacterium bifidum, is a glycoside hydrolase capable of releasing free fucose.

Exo-β-1,4-xylosidase, Bacteroides ovatus (EC.3.2.1.37), is a specialized exonuclease that targets the non-reducing end β-1,4 glycosidic bonds of xylan and xylooligosaccharides. This enzyme is Ca2+-dependent and facilitates the hydrolysis of β-1,4 glycosidic bonds through reversible metal ion binding, thereby degrading xylan to produce xylose. It is applicable in research areas such as lignocellulose bioconversion, bioethanol production, and optimization of xylan saccharification processes.

exo-β-1,3-Xylosidase, Streptomyces sp. SWU10 (EC.3.2.1.72), is an endo-xylanase capable of degrading xylan into various xylooligosaccharides.

exo-α-1,5-Arabinanase, derived from Penicillium chrysogenum, is a glycoside hydrolase enzyme that plays a role in the breakdown of arabinans. This enzyme is capable of cleaving the main chain of arabinans.

Exo-α-1,3-Mannosidase, derived from Bacteroides thetaiotaomicron, is a glycoside hydrolase enzyme that specifically targets and hydrolyzes the mannose α-1,3 linkages present in host N-glycans.

Exo-β-1,4-xylosidase, derived from Clostridium stercorarium (EC.3.2.1.37), is an exonuclease that specifically targets the β-1,4 glycosidic bonds at the non-reducing ends of xylan and xylooligosaccharides. This enzyme requires Ca2+ ions, facilitating the hydrolysis of β-1,4 glycosidic bonds through reversible metal ion binding, consequently breaking down xylan into xylose. It is utilized in fields such as lignocellulosic bioconversion, bioethanol production, and the optimization of xylan saccharification processes.

Exo-α-1,6-Mannosidase, Bacteroides thetaiotaomicron (EC 3.2.1.163), is a glycoside hydrolase that specifically hydrolyzes the mannose α-1,6 linkages in host N-glycans.

exo-α-1,2/3-Arabinofuranosidase, Penicillium oxalicum (EC.3.2.1.77), is a glycoside hydrolase enzyme that hydrolyzes the α-1,2 and α-1,3 mannose linkages in host N-glycans.

exo-α-1,2/3-Arabinofuranosidase, Bacteroides thetaiotaomicron (EC.3.2.1.55), is a glycoside hydrolase.

exo-α-1,2/3-Arabinofuranosidase, Penicillium oxalicum (EC.3.2.1.55), is a glycoside hydrolase enzyme.

Exo-α-1,3-Arabinofuranosidase, Penicillium chrysogenum (EC.3.2.1.55), is a glycoside hydrolase that cleaves the terminal 1,3-linked L-arabinofuranosyl residues in branched arabinans and arabinogalactans.

exo-α-1,2-Arabinofuranosidase, Cellvibrio japonicus (EC.3.2.1.55), is a glycoside hydrolase enzyme.

BCN-exo-PEG3-NH2 is a PEG-based PROTAC linker used in PROTAC synthesis[1].

Antibacterialagent 189 (compound 3a) is a potent antibacterial agent with high binding affinity to the target proteins OMPA/exo-1,3-β-glucanase. It demonstrates effective antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Candida albicans, and Aspergillus flavus. Additionally, Antibacterialagent 189 exhibits strong binding affinity to the target proteins SMO and SUFU/GLI-1.