ephalosporin

Cefapirin sodium is the sodium salt of Cephapirin, an antimicrobial agent.

Cephalosporin C exhibits relatively weak resistance to Gram-positive and Gram-negative bacteria. It is stable against penicillinase, but can be decomposed by cephalosporinase. When hydrolyzed to remove its side chain, it yields 7-amino-cefenoic acid (7-ACA), which is an essential raw material for the production of semisynthetic cephalosporins.

Cephalosporin Canalog-1 is an analogue of Cephalosporin C, which exhibits relatively weak resistance to both Gram-positive and Gram-negative bacteria. Cephalosporin C is stable against penicillinase but can be decomposed by cephalosporinase. Through hydrolysis, its side chain can be removed to yield 7-amino-cefenoic acid (7-ACA), an essential raw material for producing semi-synthetic cephalosporins.

Cephalosporin P1 is a biochemical.

Trans-substituted cephalosporin is an efficient inhibitor of NDM-1, demonstrating an IC50 value of 0.13 μM.

Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 µM), and this inhibition was largely attributable to the presence of zinc.

Cephalosporinase, bacillus, are enzymes produced by Bacillus; these enzymes inactivate and degrade the effectiveness of cephalosporin antibiotics. Cephalosporins are a class of β-lactam antibiotics widely used to treat bacterial infections [1].

AMG 118 Immobilized cephalosporin C acylase is an enzyme in immobilized form used primarily in industrial catalysis for the production of the vital pharmaceutical intermediate, 7-aminocephalosporanic acid (7-ACA). The CPC acylase it contains is a highly specialized β-lactam acylase or peptidase capable of cleaving the amide bond within β-lactams.

Cephalosporin Canalog-1 (sodium) is an analogue of Cephalosporin C, which demonstrates weak resistance against both Gram-positive and Gram-negative bacteria. It is stable to penicillinase and can be broken down by cephalosporinase. Hydrolysis removes the side chain to yield 7-amino-cefenoic acid (7-ACA), a crucial precursor for synthesizing semi-synthetic cephalosporins.

Cefdinir (FK-482) is a third-generation, semi-synthetic cephalosporin antibiotic effective against common bacterial infections of the ear, sinus, throat, and skin.

Cefsulodin sodium (Sulcephalosporin) hydrate is a β lactam antibiotic.

Cefmenoxime hydrochloride (Cefmenoxime hemihydrochloride) is a cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganisms, is a potent inhibitor of Enterobacteriaceae, and is highly resistant to hydrolysis by beta-lactamases. The drug has a high rate of efficacy in many types of infection and to date, no severe side effects have been noted.

Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.

Ceftibuten dihydrate (Sch-39720 dihydrate) is the dihydrate form of ceftibuten, and is a third-generation cephalosporin with antibacterial activity.

Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.

Ceftobiprole medocaril (BAL5788), the parenteral prodrug of Ceftobiprole, is a broad-spectrum cephalosporin effective against Methicillin-resistant Staphylococcus aureus (MRSA).

Cefoselis Sulfate is a widely used beta-lactam antibiotic.

Ceftobiprole (Ro 63-9141) is a β-lactam antibacterial agent that exhibits potent bactericidal activity by binding to PBPs, inhibiting transpeptidation and formation of bacterial cell walls, leading to cell lysis and death, with a MIC90 value of 2 μg/mL against methicillin-resistant Staphylococcus aureus.

AMK-EX (Immobilized cephalosporin C or 7-ACA esterase) is an immobilized enzyme where cephalosporin C/7-ACA esterases are enzymes capable of hydrolyzing cephalosporin or 7-ACA ester bonds. Immobilized enzymes involve a technique that anchors enzymes onto carriers, facilitating easy separation and recovery, while enhancing the enzyme's stability, activity, and reusability.