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Cat No. | Product Name | Synonyms | Targets |
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T1816 | (Z)-JIB-04 | NSC 693627,Z-JIB-04 | Others |
(Z)-JIB-04 (NSC 693627) is an isomer of JIB-04. | |||
T2167 | Lutidinic acid | 2,4-Pyridinedicarboxylic acid,2,4-Dicarboxypyridine,2, 4-PDCA,2,4-PDCA | Histone Methyltransferase |
lutidinic acid (2,4-Dicarboxypyridine) is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases. | |||
T13748 | L-2-Hydroxyglutaric acid disodium | (S)-2-Hydroxyglutaric acid disodium | Histone Demethylase , Mitochondrial Metabolism |
L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium) is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activ... | |||
T6545 | IOX1 | Histone Demethylase | |
IOX1 is the most effective broad-spectrum 2OG oxygenases(including the JmjC demethylases) inhibitor. The IC50 of IOX1 for KDM4A, KDM3A, is 0.6 and 0.1 uM, respectively. | |||
T6847 | GSK-J1 | GSK J1 | Histone Demethylase |
GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases. | |||
T3100 | GSK-J4 | GSK J4 HCl | Apoptosis , Histone Demethylase |
GSK-J4 (GSK J4 HCl) is a potent H3K27me3 demethylase inhibitor, with IC50s of 8.6 μM and 6.6 μM towards KDM6B and KDM6A respectively. It is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX wit... | |||
T28739 | SDZ-285604 | SDZ285604,VNF,SDZ 285604 | |
SDZ-285604 is a novel sterol 14a-demethylases (CYP51) inhibitor. | |||
T71916 | GSK-J1 sodium salt | ||
GSK-J1 sodium salt is a potent inhibitor of the H3K27 histone demethylases JMJD3 and UTX. | |||
T27070 | CPI-4203 | CPI4203,CPI 4203 | |
CPI-4203 is a selective inhibitor of KDM5 demethylases. | |||
T11475 | GSK-J1 lithium salt | Histone Demethylase | |
GSK-J1 lithium salt is an effective inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A, with an IC 50 of 60 nM for KDM6B. | |||
T11476 | GSK-J2 | Others | |
GSK-J2, an isomer of GSK-J1, haven't any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A. | |||
T11750L | KDOAM-25 trihydrochloride (2230731-99-2 free base) | KDOAM-25 trihydrochloride | Others |
KDOAM-25 trihydrochloride increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells. KDOAM-25 trihydrochloride is a potent and highly selective histone lysi... | |||
T11751 | KDOAM-25 | Antibacterial | |
KDOAM-25, a potent and highly selective inhibitor of histone lysine demethylases 5 (KDM5) with IC50 values of 71 nM for KDM5A, 19 nM for KDM5B, 69 nM for KDM5C, and 69 nM for KDM5D, enhances global H3K4 methylation at tr... | |||
T35338 | CP2 | Histone Demethylase | |
CP2 is a useful organic compound for research related to life sciences and the catalog number is T35338. | |||
T11750 | KDOAM-25 citrate | Others | |
KDOAM-25 citrate is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC 50 s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. Multiple myeloma MM1S cells treate... | |||
T73849 | KDM5-C49 hydrochloride | ||
KDM5-C49 (KDOAM-20) hydrochloride is a potent, selective inhibitor of the KDM5 family of demethylases, demonstrating IC50 values of 40 nM for KDM5A, 160 nM for KDM5B, and 100 nM for KDM5C, respectively. This compound is ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3719 | Daminozide | Succinic Acid,DMASA,Aminozide | Histone Demethylase |
Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily. | |||
T13749 | L-2-Hydroxyglutaric acid | (S)-2-Hydroxyglutaric acid | Others |
L-2-Hydroxyglutaric acid, an epigenetic modifier and potential oncometabolite in renal cancer, impedes mitochondrial creatine kinase (Mi-CK) activity, exhibiting Km and Ki values of 2.52 mM and 11.13 mM, respectively. Ad... |