dbm

DBM 1285 dihydrochloride is a p38 MAPK inhibitor.

DBM-MMAF is a drug-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody drug conjugate (ADC).

Dibutyl maleate (DBM (VAN)) is a diester of the Maleic Acid and can be used as an intermediate of the synthesis of antibacterial compounds.

DBM (C6)-VC-PAB-MMAE is a thiol-reactive Drug-linker. MMAE is an effective microtubule (tubulin) inhibitor, which is commonly used in the synthesis of antibody-drug conjugates (ADCs).

DBM-MMAE is a thiol-reactive Drug-linker. MMAE is an effective microtubule (tubulin) inhibitor, which is commonly used in the synthesis of antibody-drug conjugates (ADCs).

Compound 3a (DBM-C5-VC-PAB-MMAE) is a drug-linker conjugate designed for use in ADC synthesis. It consists of a linker with a maleimide moiety, DBM, coupled to the ADC toxin MMAE.

PTD-DBM is a competitive peptide that blocks the interaction between CXXC5 and Dvl, thereby inducing the expression of β-catenin, α-SMA, and type I collagen. Additionally, PTD-DBM promotes skin wound healing activity.

DBM-GGFG-NH-O-CO-Exatecan serves as a topoisomerase I inhibitor and can also be utilized in the synthesis of ADC molecules as a drug-linker conjugate.

DBM-819 is a biochemical.

BDBM50597431 is an NMDA receptor modulator that may have can be used to study Alzheimer's disease and Parkinson's syndrome.

DBMB is a spleen tyrosine kinase (Syk) inhibitor that significantly suppresses Syk enzyme activity. It possesses anti-inflammatory properties by inhibiting NF-κB signaling, thereby reducing the production of inflammatory mediators such as nitric oxide (NO) and prostaglandin E2 (PGE2). DBMB can be utilized in research on inflammatory diseases.

NDBM, a tumor-specific probe that targets Pim-1 kinase, exhibits heightened fluorescence upon binding and induces cytotoxicity, facilitating both cell screening and killing. It possesses targeted action on lysosomes and a sensitive pH response, enabling the monitoring of intracellular pH variations associated with autophagy and external stimuli [1].

β-Methyl L-aspartate hydrochloride (L-Aspartic acid β-methyl ester hydrochloride) is an aspartic acid derivative commonly used to synthesize various compounds and is related to body immunity and metabolism.

N-deacetylated BMS-202 is an inhibitor of PD-1/PD-L1 interactions and has potential anticancer activity for cancer research.

Dibemethine is active against chloroquinone-resistant Plasmodium falciparum by the inhibition of P. falciparum chloroquine-resistance transporter (PfCRT).

Antipain dihydrochloride (Antipain 2HCl) is a protease inhibitor derived from Actinomycetes that exhibits analgesic activity and inhibits X-ray-induced chromosomal aberrations in human lymphocytes.

AP-2238 is a bio-active chemical.

BMS-354326 is a bio-active chemical.

Poricoic acid BM is a lanostane triterpenoid found in the peels of Wolfiporia cocos mushrooms.

Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol and an anticancer agent classified as an alkylating agent. Mitobronitol exhibits myelosuppressive effects, significantly reducing the risk of several complications in allogeneic bone marrow transplantation for accelerated chronic granulocytic leukemia [1] [2].

Dibromomaleimide-C5-COOH (DBM-C5-COOH) serves as a bifunctional dibromomaleimide (DBM) linker. The compound facilitates the connection of MMAF and the synthesis of ADC [1].