chemotherapeutic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22223	3PO		Glucokinase , Autophagy
	3PO is a small-molecule inhibitor of PFKFB3 (IC50: 22.9 μM), inhibiting the proliferation of several human malignant hematopoietic and adenocarcinoma cell lines (IC50: 1.4-24 μM). It suppresses glucose uptake, and decrea...		Glucokinase , Autophagy
T20137	Dimethoate	Rogor,Phosphamid,Lurgo,L395,L 395,L-395	Others
	Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.		Others
T21435	Sulfamoxole	NSC 683535,Oxasulfa,Sulfamoxol,NSC683535,Oxazole,NSC-683535	Antibacterial
	Sulfamoxole (Sulfamoxol) is an antibacterial belonging to sulfonamide.		Antibacterial
TN2264	Terpinen-4-ol	Terpinine-4-ol,4-Carvomenthenol	Others , Endogenous Metabolite
	Terpinen-4-ol (4-Carvomenthenol) is a natural product from Pimpinella yunnanensis.		Others , Endogenous Metabolite
T16045	Methotrexate metabolite	DAMPA	Antifolate , Drug Metabolite
	Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant.		Antifolate , Drug Metabolite
T11373	GCN2-IN-1	A-92	Others
	GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.		Others
T1892	Kobe2602		Raf , Ras
	Kobe 2602 is an inhibitor of Ras that exhibits anticancer chemotherapeutic activities.		Raf , Ras
T2788	Baccatin III	Baccatin Ⅲ	Others
	Baccatin III (Baccatin Ⅲ) is a polycyclic diterpene which can be used for the semi-synthesis of paclitaxel and analogs. It has immunomodulatory and anticancer chemotherapeutic activities.		Others
T2158	Nutlin-3	Nutlin3	E1/E2/E3 Enzyme
	Nutlin-3 is an MDM2 antagonist.Nutlin-3 inhibits the MDM2-p53 interaction (IC50: 0.09 μM) and activates p53. Antiproliferative agent; chemotherapeutic agent; induces apoptosis in Y cells.		E1/E2/E3 Enzyme
T16349	NSC-60339		Others , Antibacterial
	NSC-60339 is an inhibitor of efflux pump, and a substrate of AcrAB-TolC, is a polybasic terephthalic acid derivative studied as a potential cancer chemotherapeutic agent.		Others , Antibacterial
T0951	Hydroxychloroquine sulfate	Acidum iopanoicum,HCQ sulfate	DNA , SARS-CoV , TLR , Parasite , Autophagy
	Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in ...		DNA , SARS-CoV , TLR , Parasite , Autophagy
T1082	Benzyl isothiocyanate	Benzoylthiocarbimide,Isothiocyanic Acid Benzoyl Ester	Apoptosis , Antibacterial , Antibiotic
	Benzyl isothiocyanate (Benzoylthiocarbimide) (BITC) is an isothiocyanate originally found in cruciferous vegetables. It shows immunomodulatory, anti-parasitic, antibiotic, antioxidative, anti-atherosclerotic, anti-angiog...		Apoptosis , Antibacterial , Antibiotic
T5753	Flavokawain C		Apoptosis
	Flavokawain C (FKC), a naturally occurring chalcone, which can be isolated from Kava.FKC has the potential to be developed into chemotherapeutic drug for the treatment of colon adenocarcinoma.		Apoptosis
TMS0484	Episyringaresinol 4'-O-β-D-glncopyranoside	(-)-Syringaresinol 4-O-β-D-glucopyranosi	Others
	Episyringaresinol 4'-O-β-D-glncopyranoside ((-)-Syringaresinol 4-O-β-D-glucopyranosi) inhibits the proliferation of human promyelocytic HL-6 cells through G(1) arrest and induction of apoptosis, may be a potential chemot...		Others
TP1792L	KKI-5 acetate(97145-43-2 free base)		Serine Protease
	KKI-5 acetate is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.		Serine Protease
T8979	AEM1		Nrf2
	AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibit...		Nrf2
T72024	ZIM
	ZIM, a norbornene derivative of 4-Aminoantipyrine, effectively induces DNA damage, leading to genomic and chromosomal alterations, cell death, and phagocytosis activation. Its properties highlight its potential as a chem...
T6S1683	Demethoxycurcumin	Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin	Apoptosis , Antioxidant , Antibacterial , Autophagy
	1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic e...		Apoptosis , Antioxidant , Antibacterial , Autophagy
T15771	Lobaplatin	D-19466	DNA Alkylation
	Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent which shows activity for a variety of tumour types and is a ...		DNA Alkylation
T6S1027	Tussilagone		Others
	1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human co...		Others