as-85

AS-85 is a cell permeable ASH1L inhibitor with anti-leukemic activity, inhibits the growth of leukemic cells, increases cLogP, decreases tPSA, and can be used in the study of leukemia.

Litoxetine is a selective 5-HT uptake inhibitor and is a 5-HT3 receptor antagonist. Litoxetine acts as an antidepressant and has shown antiemetic properties in ferrets. Litoxetine (1 and 10 mg/kg i.v.) dose-dependently reduced the number of regurgitations and vomiting and delayed the onset of vomiting. Litoxetine has an affinity for brain 5HT3 receptors (Ki = 85 nM).

JNJ-54717793 is an orally active, brain-penetrating compound that acts as a selective and high-affinity antagonist of the orexin-1 receptor (OX1R) with a plasma EC50 of 85 ng/mL. It demonstrates K_i values of 16 nM for hOX1R (human OX1R) and 700 nM for hOX2R, indicating its strong preference for hOX1R over hOX2R. JNJ-54717793 is recognized for its effectiveness in the treatment of anxiety disorders.

Compound Fr12151, with CAS No. 25462-85-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12151 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr12559, with CAS No. 1204-85-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12559 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr13129, with CAS No. 20699-85-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13129 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr13250, with CAS No. 140695-85-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13250 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr13751, with CAS No. 1074-85-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13751 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr13876, with CAS No. 54401-85-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13876 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr13994, with CAS No. 694-85-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13994 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14071, with CAS No. 4858-85-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14071 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr14330, with CAS No. 15871-85-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14330 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-Hydroxy-2-methylindole, with CAS No. 13314-85-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Hydroxy-2-methylindole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound PDK0074, with CAS No. 1484-85-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0074 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound PDK0366, with CAS No. 826-85-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0366 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound PDK0377, with CAS No. 85-18-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0377 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.

2,4'-Dichlorobenzophenone, with CAS No. 85-29-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2,4'-Dichlorobenzophenone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr12194, with CAS No. 120107-85-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12194 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr12195, with CAS No. 56643-85-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12195 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr12223, with CAS No. 17920-85-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12223 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr12363, with CAS No. 690632-85-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12363 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr12567, with CAS No. 63968-85-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12567 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Compound Fr12909, with CAS No. 376637-85-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12909 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.