as-35

AS-35 is an orally effective, potent, and selective antagonist of leukotrienes, antagonizing LTC4-, LTD4-, and LTE4-induced ileum contractions with IC50 values of 8 nM, 4 nM, and 3 nM, respectively. It exhibits antiallergic activities.

As-358 exhibits inhibitory effects against the Ebola virus (IC50 = 47.5 μM) and the Marburg virus (IC50 = 3.7 μM) [1].

As-358 (hydrochloride) shows well in vivo safety as well as inhibits Ebola virus and Marburg virus with IC 50 values of 9.1 μM and 18.1 μM [1].

Bentazone is a selective post-emergence herbicide that interferes with photosynthesis, used to suppress broadleaf weeds and sedges.

5-(N,N-Hexamethylene)-amiloride (5-HMA) is an amiloride derivative that inhibits TRPA1-mediated calcium signaling (IC50: 35 μM). It functions as an inhibitor of the Na+/H+ exchanger (NHE) with Ki values ranging from 0.013 to 2.4 μM for various NHE isoforms. Additionally, 5-HMA blocks ASIC3 channels by 51% at 20 μM.

4,4'-Dimethyl-2,2'-bipyridine ,with CAS No. 1134-35-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4,4'-Dimethyl-2,2'-bipyridine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Pyrrolidine-2-thione ,with CAS No. 2295-35-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Pyrrolidine-2-thione provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Methyl 2-fluorobenzoate ,with CAS No. 394-35-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Methyl 2-fluorobenzoate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Chloroquinoline ,with CAS No. 611-35-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Chloroquinoline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Amino-6-methoxypyridine ,with CAS No. 17920-35-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Amino-6-methoxypyridine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-(3-Chlorophenyl)propan-1-one ,with CAS No. 34841-35-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-(3-Chlorophenyl)propan-1-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5,6,7,8-Tetrahydro-1-naphthol ,with CAS No. 529-35-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5,6,7,8-Tetrahydro-1-naphthol provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Mercaptoimidazole ,with CAS No. 872-35-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Mercaptoimidazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Lycopene (ψ,ψ-Carotene) is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as tomatoes, pink grapefruit, apricots, red oranges, watermelon, rosehips, and guava. As a class, carotenoids are pigment compounds found in photosynthetic organisms (plants, algae, and some types of fungus), and are chemically characterized by a large polyene chain containing 35-40 carbon atoms; some carotenoid polyene chains are terminated by two 6-carbon rings. In animals, carotenoids such as lycopene may possess antioxidant properties which may retard aging and many degenerative diseases. As an essential nutrient, lycopene is required in the animal diet.

Aleuritic Acid (9,10,16-trihydroxy-palmitic acid), or α-aleuritic acid, is a major ingredient in shellac, constituting about 35% of it. It is used as a starting material in the perfume industry for the preparation of musk aroma.

(E)-3-(p-Tolyl)acrylaldehyde is a cinnamaldehyde and endogenous metabolite commonly used as a food flavoring with inhibitory effect on Coxsackievirus B3 (CC50=3.96 μM), which can be used in biochemical experiments and organic synthesis.

2-Benzylbenzoic acid ,with CAS No. 612-35-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Benzylbenzoic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(3S)-3-(4-Hydroxyphenyl)-4-hexynoic acid ,with CAS No. 865233-35-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (3S)-3-(4-Hydroxyphenyl)-4-hexynoic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Methyl-4-(3-pyridyl)thiazole ,with CAS No. 122845-35-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Methyl-4-(3-pyridyl)thiazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(5-Methyl-1-phenyl-1H-pyrazol-4-yl)methanol ,with CAS No. 153863-35-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (5-Methyl-1-phenyl-1H-pyrazol-4-yl)methanol provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

N1-(1-oxo-2,3-dihydro-1H-inden-5-yl)acetamide ,with CAS No. 58161-35-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N1-(1-oxo-2,3-dihydro-1H-inden-5-yl)acetamide provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-(Tetrahydropyran-4-yloxy)aniline ,with CAS No. 898289-35-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-(Tetrahydropyran-4-yloxy)aniline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(2-Thiomorpholinopyrid-4-yl)methylamine ,with CAS No. 886851-35-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (2-Thiomorpholinopyrid-4-yl)methylamine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

1-Butyl-3-(3-methoxyphenyl)thiourea ,with CAS No. 22244-35-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-Butyl-3-(3-methoxyphenyl)thiourea provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.