aporphine

(+)-Magnoflorine (Thalictrin) has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mechanism other than prevention of micelle formation or protection of the erythrocyte membrane against osmotic imbalance.

2,3,5,6-Tetramethoxyaporphine, a benzyl isoquinoline alkaloid with antitussive properties, can be extracted from Glaucium flavum Cr. (Family Papaveraceae) [1] [2].

2-Hydroxy-1-Methoxyaporphine can inhibit CYP2D6 activity, it also increase the glucose consumption significantly as rosiglitazone.

1,2,3,10-Tetramethoxy-9-(2-hydroxy-4,5-dimethoxybenzyloxy)oxoaporphine is a natural product of Hernandia, Hernandiaceae. The catalog number is TN2479, and the CAS number is 872729-33-4. It can be used as a reference standard.

6-Formyl-1,2,9,10-tetramethoxy-6a,7-dehydroaporphine is a natural product from Aconitum carmichaelii.

1,2-Methylenedioxy-3,10,11-trimethoxyaporphine exerts moderate vessel-relaxing activities with the IC 50 value from 16.50 to 32.81 microM at the test concentrations.

N-Nornuciferine hydrochloride(4846-19-9 free base) (N-Nornuciferine hydrochloride) is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).

Lanuginosine, an aporphine alkaloid, exhibits cytotoxicity against U251.

(+)-Magnoflorine iodide (Thalictrine iodide) has anti-inflammatory activity, it can inhibit inflammations.

(+)-N-Formylnorglaucine, an aporphine alkaloid found in the leaves of Unonopsis stipitata, features a formyl group that is connected to the nitrogen within its heterocyclic structure.

(+)-Magnoflorine chloride (Escholine chloride) has anti-inflammatory activity, it can inhibit inflammations.

Xylopine, an aporphine alkaloid, exhibits cytotoxic effects on cancer cells by inducing oxidative stress, provoking G2 M cell cycle arrest, and triggering apoptosis [1].

Oxocrebanine, an aporphine alkaloid present in Fissistigma poilanei (Annonaceae) [1], is identified as a constituent of this botanical species.

N-Methylcorydine, an aporphine alkaloid (+)[1], is a chemical compound.

Filiformine is a natural aporphine alkaloid with an oxo group.

O-Methylcassythine is an aporphine alkaloid isolated from Cassytha filiformis, exhibiting vasodilatory activity.

(+)-N-Methylhernovine is an aporphine alkaloid that can be isolated from Hernandia nymphaeifolia. It exhibits mild cytotoxicity against cancer cells.

N-Nornuciferine, an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).