andrographolide

Andrographolide (Andrographis)(Andrographis), an irreversible antagonist of NF-κB, has anti-inflammatory and anti-platelet aggregation activities and potential antineoplastic.

Andrographolide-lipoic acid is an analogue of Andrographolide, synthesized through the conjugation of Andrographolide and Lipoic acid. It inhibits NF-κB and exhibits anti-diabetic effects as well as protective effects on β-cells.

Neoandrographolide (Neoandrographiside) has potent hypolipidemic effect and protects the cardiovascular without significant liver damage.Neoandrographolide has anti-inflammatory effect, might result from inhibition of iNOS and COX-2 expression through inhibiting p38 MAPKs activation.Neoandrographolide as chemosensitizer in S-Jurkat and X chromosome-linked inhibitor of apoptosis protein (XIAP)-overexpressing Jurkat cells, a model for chemoresistance.

14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.

14-Deoxy-11-oxoandrographolide is a natural product from Andrographis paniculata

Bisandrographolide A activates TRPV4 channels, could play a role in some of the effects of Andrographis extract described in traditional medicine.

14-Epiandrographolide is a compound derived from the above-ground parts of Andrographis paniculata that induces cell differentiation and can be used in the study of multiple sclerosis.

14-Deoxy-12-hydroxyandrographolide is a natural product of Andrographis (Acanthaceae), with catalog number TN5586 and CAS number 219721-33-2. It can be used as a reference standard.

14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release.

14-Deoxy-17-hydroxyandrographolide is a natural product of Andrographis, Acanthaceae. The catalog number is TN2623 and the CAS number is 869384-82-7. 14-Deoxy-17-hydroxyandrographolide can be used as a reference standard.

Isoandrographolide, a compound known for its cell differentiation-inducing and hepatoprotective effects, also inhibits NLRP3 inflammasome activation and mitigates silicosis in mice.

Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees.

Deoxyandrographolide (14-deoxyandrographolide) potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory mediators TNF-α and IL-6.

Bisandrographolide C is identified from Andrographis paniculata. Bisandrographolide C activates TRPV1 and TRPV3 channels (Kds: 289 and 341 μM) and protects cardiomyocytes from hypoxia-reoxygenation injury.

14-Deoxy-11-hydroxyandrographolide shows potent cell differentiation-inducing activity towards mouse myeloid leukemia (M1) cells.

Dehydroandrographolide Succinate is a traditional Chinese medicine used in the treatment of pneumonia, respiratory tract infection.