american

(-)-Epipodophyllotoxin (2) is an antiproliferative agent targeting cancer cells, exhibiting GI50 values of 0.36 μM in HeLa cells and 0.24 μM in MCF-7 cells, and inhibiting mitotic spindle assembly in vitro.

ENT 25641 is a bio-active chemical. Detailed information has not been published.

Americanol A enhances choline acetyltransferase activity; has neurotrophic properties.

Americanin A natural thrombin inhibitor, suppressing melanin synthesis, regulating the ATM/ATR signaling pathway and the Skp2-p27 axis in human colon cancer cells.

Phytolacca americana Lectin (PWM) is a lectin specific for carbohydrates containing N-acetylglucosamine. It stimulates peripheral lymphocytes to undergo mitosis by binding to the cell surface. Phytolacca americana Lectin can serve as a probe for specific binding to biomolecules and is useful as a biomaterial or organic compound in life science research.

Furanones (HDMF) are mainly derived from American grape (Vitis labrusca) and its hybrid varieties. As an important aroma compound in fruits, it exhibits strawberry-like aroma characteristics in some wines.

BiPNQ is a Trypanosoma cruzi inhibitor. Trypanosoma cruzi is the etiological agent of Chagas disease (American trypanosomiasis).

Akagerine is derived from the root bark of South American Strychnos.

Cyloone is a bio-active chemical. Detailed information has not been published.

Loline is a natural insecticidal and deterrent to a broad range of insects, including species in the Hemiptera, Coleoptera, Hymenoptera, Lepidoptera, and Blattodea orders. Loline deters species such as the bird cherry-oat aphid (genus Rhopalosiphum), larg

Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditions. A receptor for the AGEs (RAGE) binds certain members of this class to initiate cell signaling.[1][2] Pentosidine is a well-characterized natural AGE that is often used as a biomarker for the production of all AGEs. While pentosidine can be measured in urine, the majority of this AGE is catabolized before excretion.[3] Reference:[1]. Neeper, M., Schmidt, A.M., Brett, J., et al. Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. The Journal of Biological Chemisty 267(21), 14998-15004 (1992).[2]. Brett, J., Schmidt, A.M., Yan, S.D., et al. Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues. American Journal of Pathology 143(6), 1699-1712 (1993).[3]. Miyata, T., Ueda, Y., Horie, K., et al. Renal catabolism of advanced glycation end products: The fate of pentosidine. Kidney International 53, 416-422 (1998).

Pseudoginsenoside F11 (Ginsenoside A1) is a component of Panax quinquefolium (American ginseng) which main pharmacological activities are positive inotropic effect on isolated heart function, good therapeutic effect on myocardial ischemia, and good protective effect on cardio-cerebrovascular system and nervous system.

D-Luciferin 6′-methyl ether (also known as 6′-Methoxyluciferin or compound 19a) is a highly effective inhibitor of luciferase obtained from the North American firefly Photinus pyralis (PpyLuc), exhibiting an IC50 value of 0.1 μM. This analog of D-luciferin interacts non-specifically with the ATP and luciferin binding sites within the active site of PpyLuc.

Pseudin-2, an antimicrobial peptide (AMP) isolated from the skin of the South American paradoxical frog (Pseudis paradoxa), demonstrates a potent inhibitory effect on the growth of Gram-negative bacteria [1].

Dihydrobaicalin, a flavonoid glycoside, is isolated from the American skullcap (Scutellaria lateriflora L.) [1].

Dermaseptin-B5, an antimicrobial peptide sourced from the skin secretions of the South American frog Phyllomedusa bicolor, exhibits potent antimicrobial activity [1].

Dermaseptin-B4 is a potent antimicrobial peptide sourced from the skin secretions of the South American frog, Phyllomedusa bicolor [1].

D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) sodium serves as a potent inhibitor of the North American firefly Photinus pyralis (PpyLuc) luciferase, exhibiting an IC50 of 0.1 μM. As an analog of D-luciferin, this compound demonstrates non-specific interactions at the ATP- and luciferin-binding sites within the active site of PpyLuc [1].

Anti-Mouse Delta-like protein 1/DLL1 Antibody (HMD1-5) is an IgG, κ inhibitor antibody derived from the American hamster, targeting mouse δ-like protein 1/DLL1.

Anti-Mouse TCRβ Antibody (HB218) is an IgG antibody inhibitor derived from American hamster, specifically targeting mouse TCRβ.

Anti-Mouse Delta-like protein 4/DLL4 Antibody (HMD4-2) is an IgG, κ antibody inhibitor derived from the American hamster, targeting mouse δ-like protein 4/DLL4.

The Anti-Mouse Notch4 Antibody (HMN4-14) is an IgG, κ antibody inhibitor derived from an American hamster, targeting the Notch4 protein in mice.

Anti-Mouse Jagged 2 Antibody (HMJ2-1) is an IgG antibody inhibitor derived from American hamster, specifically targeting mouse Jagged 2.

Anti-Mouse CD48 Antibody (HM48-1) is an IgG antibody inhibitor derived from the American hamster, targeting mouse CD48.