alpha-ketoglutaric acid

2-Ketoglutaric acid Sodium (AKG) is a key molecule in the TCA cycle. It can be produced from glutamate by oxidative deamination via glutamate dehydrogenase and as a product of pyridoxal phosphate-dependent transamination reactions (mediated by branched-chain amino acid transaminases) in which glutamate is a common amino donor.

2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC50=15 mM) and exhibits antioxidant activity. As an intermediate in the Krebs cycle, 2-Ketoglutaric acid can generate ATP or GTP. 2-Ketoglutaric acid also serves as the primary carbon skeleton for nitrogen assimilation reactions.

Alpha-Ketoglutaric Acid-[1,2-13C2] (Standard) is a reference standard of Alpha-Ketoglutaric Acid-[1,2-13C2] intended for quantitative analysis, quality control, and related biochemical research applications.

2-Ketoglutaric acid potassium (Alpha-Ketoglutaric acid potassium) is an intermediate in the Krebs cycle where ATP or GTP is produced. It also serves as the primary carbon backbone in nitrogen assimilation reactions. Additionally, 2-Ketoglutaric acid potassium acts as a reversible inhibitor of tyrosinase with an IC50 value of 15 mM.

Glutamate dehydrogenase, an enzyme found in prokaryotes and eukaryotic mitochondria, facilitates the enzymatic determination of ammonia, alpha-ketoglutaric acid, L-glutamate, and urease [1].

2-Ketoglutaric acid-D4 is a deuterated form of 2-Ketoglutaric acid. 2-Ketoglutaric acid (T5980) (Alpha-Ketoglutaric acid) functions as an intermediate in the Krebs cycle where ATP or GTP is generated. It also serves as a primary carbon skeleton for nitrogen assimilation reactions. Additionally, 2-Ketoglutaric acid (T5980) acts as a reversible inhibitor of tyrosinase (IC50=15 mM).

2-Ketoglutaric acid-13C5 is the 13C labeled form of 2-Ketoglutaric acid. This compound, also known as Alpha-Ketoglutaric acid, serves as an intermediate in the Krebs cycle for ATP or GTP production. Additionally, it acts as a principal carbon skeleton for nitrogen assimilation reactions. 2-Ketoglutaric acid (T5980) is a reversible inhibitor of tyrosinase (IC50=15 mM).

2-Ketoglutaric acid-D6 is the deuterium-labeled form of 2-Ketoglutaric acid. Also known as Alpha-Ketoglutaric acid, it serves as an intermediate in the Krebs cycle for the production of ATP or GTP. This compound also acts as a primary carbon skeleton in nitrogen assimilation reactions. Furthermore, 2-Ketoglutaric acid (T5980) functions as a reversible inhibitor of tyrosinase with an IC50 of 15 mM.