T1249

Beclamide (Chlorakon) (N-benzyl-B-chloropropionamide) is a drug that possesses anticonvulsant activity. It is no longer used. It has been used as a sedative and as an anticonvulsant. It was studied in the 1950s for its anticonvulsant properties, as a treatment for generalized tonic-clonic seizures. It was not effective for absence seizures.

Pivagabine (CXB-722), a hydrophobic 4-aminobutyric acid derivative, exhibits neuromodulatory activity and successfully penetrates the blood-brain barrier in rats. It counteracts the impact of foot shock on GABAA receptor function and corticotropin-releasing factor (CRF) levels in the rat brain.

Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1 and AHR, with potential for blood-brain barrier permeability.

Pitavastatin lactone is the major metabolite of Pitavastatin in humans.Pitavastatin is a competitive inhibitor of HMG-CoA reductase.

Pitolisant oxalate is a potent and selective nonimidazole inverse agonist of the recombinant human histamine H3 receptor, exhibiting a Ki of 0.16 nM.

Malonomicin is a useful organic compound for research related to life sciences and the catalog number is T124924.

PK68 is an effective and selective inhibitor of type II receptor-interacting kinase 1 (RIPK1, IC50 = 90 nM). PK68 can be used for research on the treatment of inflammatory disorders and cancer metastasis.

Isorhamnetin 3-glucuronide is a useful organic compound for research related to life sciences and the catalog number is T124938.

PKC-IN-1 is an ATP-competitive and reversible conventional PKC enzymes inhibitor (PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε with IC50s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM, respectively).

Broussonol E is a useful organic compound for research related to life sciences and the catalog number is T124945.

PKC-theta inhibitor 1 is an inhibitor of PKCθ (Ki of 6 nM)

Pterosin A is a useful organic compound for research related to life sciences and the catalog number is T124961.

PKR activator 1 is a potent activator of pyruvate kinase-R (PKR).

Natsudaidain is a useful organic compound for research related to life sciences and the catalog number is T124974.

PKR activator 2 is a potent activator of pyruvate kinase-R (PKR).

PKR-IN-2 is a activator of pyruvate kinase (PKR).

Tirandamycin A is a useful organic compound for research related to life sciences and the catalog number is T124996.