Ophiopogon

Prosapogenin A (Progenin III) has anticancer activity.

Methylophiopogonone A is an isoflavone isolated from the roots of Ophiopogon japonicas with anti-inflammatory properties.

1. Neoruscogenin represents a universal pharmacological tool for RORα research due to its specific selectivity profile versus other nuclear receptors.

Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside) is a natural product with significant pharmacological effects on the cardiovascular system.

1. Methylophiopogonanone B (MOPB) induces cell morphological change and Rho activation via melanocyte dendrite retraction and stress fiber formation.

Ophiopogonin D' can activate SIRT1 in a dose-dependent manner. Ophiopogonin D' also noncompetitively inhibits UGT1A6 and UGT1A10.

1. Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties. 2. Methylophiopogonanone A has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulating the expression of MMP-9 and tigh

1. Ruscogenin has anti-inflammatory activity, suppressed zymosan A-evoked peritoneal total leukocyte migration in mice in a dose-dependent manner, 2. Ruscogenin inhibited adhesion of leukocytes to a human umbilical vein endothelial cell line (ECV34) injured by tumor necrosis factor-alpha (TNF-alpha) in a concentration-dependent manner. 3. Ruscogenin significantly attenuate LPS-induced acute lung injury via inhibiting expressions of TF and iNOS and NF-kappa B p65 activation.

Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation. Ophiopogonin D(OPD) significantly inhibited the in vitro and in vivo growth of prostate cells via RIPK1, OPD may be developed as a potential anti-prostate cancer agent.

Ophiopogonin C' pharmacological activities may be related to the substances in nucleus mainly.

14-Hydroxy sprengerinin C, a natural product derived from Ophiopogon japonicus.

Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of TF and IL-6.

Liriopesides B (Nolinospiroside F) exhibited potential anticancer activity against human ovarian cancer A2780 cells.

17-Hydroxy sprengerinin C is a glycoside compound isolated from rhizomes of Polygonatum sibiricum with stronger anticancer activities. 17-Hydroxy sprengerinin C reduces the expression of Blc-2 and pro-caspase3 and increases the production of Bax.

Menisdaurin is a cyanogenic glycoside natural product isolated from the plant species Flueggea virosa, and its purported anti-viral pharmacological activities have been analytically characterized and quantified through an ultra-performance liquid chromatography with photodiode array detection (UPLC-PDA) method.

Securinol A (Virosine B) is an alkaloid isolated from Securinega suffruticosa Rehd, with potential antimicrobial activity.

Cixiophiopogon A is a natural product from Ophiopogon japonicus.

Ophiopogonin B has antitumor activity and is a prospective inhibitor of PI3K/Akt.

3-(2,4-Dihydroxybenzyl)-5-hydroxy is a natural product for research related to life sciences. The catalog number is TN2848 and the CAS number is 149180-48-3.

Ophiopogonanone F can be used for preparing a drug for resisting hepatocellular injury.

5,7-Dihydroxy-3-(4-hydroxy-3,5-diMethoxybenzyl)-6,8-diMethylchroMan-4-one has oxygen free radicals (OFRs) scavenging effects, it can scavenge hydroxyl radical and hydrogen peroxide in vitro. It shows a strong cytotoxic activity on HeLa-S3 cell.

6-Aldehydo-isoophiopogonone A is a natural product of Ophiopogon, Liliaceae. The catalog number is TN5470 and the CAS number is 112500-90-0. 6-Aldehydo-isoophiopogonone A can be used as a reference standard.

Ophiopogonoside A is a natural product of Ophiopogon, Liliaceae. The catalog number is TMA2212 and the CAS number is 791849-22-4. Ophiopogonoside A can be used as a reference standard.

Ophiopogonanone C is a natural isoflavone isolated from Ophiopogon japonicas, suitable for biochemical experiments and drug synthesis research.