1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inflammatory mediators via NF-κB inactivation, and support its possible therapeutic role in colitis. 4. Monotrope ininhibit the expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) mRNA in LPS-induced RAW 264.7 macrophages.
Fructo-oligosaccharide DP10/GF9 is a fructan with a degree of polymerisation (DP) of 10, consisting of one D-glucose (Glucose) unit at the non-reducing end and nine fructose (Fructose) units linked by (2→1)-β-glycosidic bonds.
Damnacanthal is a natural anthraquinone compound with potential anticancer, anti-inflammatory, antioxidant, anti-malarial, and antiviral effects.Damnacanthal inhibits a variety of protein kinases such as LIMK1 (IC50=0.8 μM), LIMK2 (IC50=1.5 μM), and Lck (IC50=17 nM), and inhibits the growth of human hepatocellular carcinoma (SKHep-1) and human breast cancer (MCF-7) cells.
2-Hydroxy-3-(hydroxymethyl)anthraquinone exhibits quinone reductase (QR)- inducing activity in Hepa lclc7 cells, with the concentration required to double QR activity of 0.94 microM.
Fructo-oligosaccharide DP11/GF10 is a fructooligosaccharide (FOS) with a high degree of polymerization of approximately 11. It consists of multiple fructose units linearly linked via β(2→1) glycosidic bonds, with a glucose residue at the terminal end of the molecule. Fructo-oligosaccharide DP11/GF10 belongs to prebiotic substrates and can be selectively utilized by gut microbiota to modulate the structure and metabolic activity of the intestinal flora.
Fructo-oligosaccharide DP13 is a high-degree polymerization fructan that belongs to the inulin-type polysaccharides. It can be isolated from Morinda officinalis.