1. Humantenmine is a toxic compound isolated from Gelsemium elegans Benth . 2. Humantenmine and koumine may inhibit several CYP450 enzyme activities.

1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic effect in rodent behavioral models of inflammatory and neuropathic pain, the m

Sempervirine can unwind circular DNA, it shows selective inhibition of in vitro synthesis of cancer DNA .

16-Epivoacarpine is a natural product from Gelsemium elegans.

Gelsevirine, a novel STING-specific inhibitor, is an alkaloid from Gelsemium elegans with anxiolytic and antiproliferative activities that inhibits interferon and inflammatory cytokine induction in macrophages exposed to STING agonists, and attenuates STING-related inflammation in sepsis.

1. Gelsemine (Gelsemin) has antitumor activity. 2. Gelsemine has anti-oxidative activity. 3. Gelsemine has anti-hyperlipidemic activity. 4. Gelsemine has marked antinociception in inflammatory, neuropathic and bone cancer pains without inducing antinociceptive tolerance.

Humantenine, a naturally occurring indole alkaloid derived from *Gelsemium elegans*, HCT116 cell injury induced by humantenine was associated with the abnormal mRNA expression of m6A regulators

Sempervirine nitrate is an alkaloid extracted from Gelsemium elegans Benth., inhibiting HCC tumor growth and enhancing sorafenib's antitumor effects in vivo. It inhibits HCC proliferation and induces apoptosis by modulating the Wnt/β-catenin pathway.

Humantenidine is a natural product of Gelsemium, Loganiaceae. The catalog number is TN1746 and the CAS number is 114027-39-3. Humantenidine can be used as a reference standard.

11-Hydroxyrankinidine is a natural product for research related to life sciences. The catalog number is TN2586 and the CAS number is 122590-03-8.

Gelsempervine A is a natural product from Gelsemium elegans.

Humantenirine is an indolone alkaloid discovered in Gelsemium elegans, suitable for biochemical experiments and drug synthesis research.

11-Hydroxyhumantenine is a natural product of Gelsemium, Loganiaceae. The catalog number is TN6035 and the CAS number is 122590-04-9. 11-Hydroxyhumantenine can be used as a reference standard.

16-Epikoumidine is a natural product for research related to life sciences. The catalog number is TN6036 and the CAS number is 124096-81-7.

N-Methoxyanhydrovobasinediol is an alkaloid isolated from Gelsemium elegans, applicable for biochemical experiments and drug synthesis research.

(Z)-Akuammidine is a natural product

Koumine N-oxide is a natural product from Gelsemium elegans.

11-Hydroxygelsenicine is a natural product of Gelsemium, Loganiaceae. The catalog number is TN6031 and the CAS number is 1195760-68-9. 11-Hydroxygelsenicine can be used as a reference standard.