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Sodium ion indicator

Sodium ion indicators are a type of fluorescent dye used to detect changes in sodium ion concentration inside and outside cells. They achieve quantitative analysis by binding to sodium ions to trigger changes in optical signals. They are widely used in neurophysiology and drug development.

  • SBFI AM
    T37473129423-53-6
    SBFI AM is a membrane-permeant, fluorescent Na+ indicator dye. It is selective for Na+ over K+ with Kd values of 20 and 120 mM for these ions, respectively. [1]Increasing concentration of Na+ increases the ratio of excitation efficiency at 330-345 nm to that at 370-390 nm with emission collected at 450-550 nm. [1] Therefore, ratio fluorometry and imaging can be performed with the same wavelengths. SBF AM is suitable for single intracellular dye injection and is typically used for high-resolution measurements of Na+ concentration in intact tissue through two-photon confocal imaging.[2]
    • $1,730
    35 days
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  • ING-2 AM
    T839431642554-49-1
    ING-2 AM is a membrane-permeable fluorescent indicator specifically designed for sodium ions (Na+), exhibiting a binding affinity with a dissociation constant (Kd) of 20 mM. With excitation and emission maxima (λ) at 525 nm and 545 nm respectively, this compound achieves a 20-fold selectivity over potassium ions (K+). It is utilized both in vitro and in situ to monitor real-time sodium influx.
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    3-6 months
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  • SBFI tetraammonium
    T87369172651-12-6
    SBFI (tetraammonium), a sodium-sensitive fluorescence indicator and the tetraammonium salt of SBFI, operates effectively at an excitation wavelength of 333 nm and an emission wavelength of 539 nm [1].
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  • SBFI
    T87370124549-08-2
    SBFI is a membrane-permeant fluorescent Na+ indicator dye, excited at 340 nm with emission collected at 450 nm [1]. It selectively indicates Na+ over K+ with Kd values of 20 mM and 120 mM for these ions, respectively [2].
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