T10081 |
Thrombin inhibitor 1
|
855998-46-8
|
98%
|
|
Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).
|
T12782 |
RWJ-445167
|
226566-43-4
|
98%
|
|
RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.
|
T12301 |
OM-189
|
55381-18-5
|
98%
|
|
OM-189 is a selective inhibitor of synthetic thrombin.
|
T16377 |
Odiparcil
|
137215-12-4
|
98%
|
|
Odiparcil is an orally active beta-d-thioxyloside analog. Odiparcil is an indirect thrombin inhibitor that exerts its anticoagulant effect through activation of ...
|
T16292 |
NFPS
|
405225-21-0
|
98%
|
|
NFPS exerts neuroprotection via glyR alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion. NFPS is a selective and non-competiti...
|
T41031 |
Protamine sulfate
|
9009-65-8
|
98%
|
|
Protamine sulfate, a cationic peptide, is an anti-heparin compound that enhances lipid-mediated gene transfer and neutralizes the anticoagulant effect of heparin...
|
T22323 |
Enoxaparin sodium
|
679809-58-6
|
98%
|
|
Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment my...
|
T22246 |
Argatroban Monohydrate
|
141396-28-3
|
98%
|
|
Argatroban Monohydrate is a specific thrombin inhibitor, which is a non-heparin anticoagulant, prevents the formation of thrombi.
|
T68086 |
Imitrodast
|
114686-12-3
|
98%
|
|
Imitrodast is a small molecule thromboxane A2 synthase (TXA2 synthase) inhibitor for the treatment of immune system disorders, respiratory disorders, and cardiov...
|
T17265 |
Ximelagatran
|
192939-46-1
|
98%
|
|
Ximelagatran, a direct thrombin inhibitor, can be taken orally and acts solely by inhibiting the actions of thrombin. Ximelagatran is converted to the active age...
|
T11994 |
Melagatran
|
159776-70-2
|
98%
|
|
Melagatran, a direct and orally active thrombin inhibitor, specifically inhibits thrombin without affecting other enzymes in the coagulation cascade or fibrinoly...
|
T6295 |
Dabigatran
|
211914-51-1
|
98%
|
|
Dabigatran is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the ri...
|
T10951 |
Dabigatran ethyl ester hydrochloride
|
211914-50-0
|
98%
|
|
Dabigatran ethyl ester hydrochloride is an effective inhibitor of ribosyl dihydronicotinic acid amide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and is a ...
|
T5519 |
Bivalirudin
|
128270-60-0
|
98%
|
|
Bivalirudin is a reversible inhibitor of α- and ζ-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clotting activities.
|
T0449 |
Menadione
|
58-27-5
|
98%
|
|
Menadione is a synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after ...
|
T0389 |
Dabigatran etexilate
|
211915-06-9
|
98%
|
|
Dabigatran is a thrombin inhibitor, which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation.
|
T67959 |
Pirodomast
|
108310-20-9
|
98%
|
|
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is wea...
|
T7417 |
Avatrombopag
|
570406-98-3
|
98%
|
|
Avatrombopag is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiation and platele...
|
T6236 |
Ozagrel
|
82571-53-7
|
98%
|
|
Ozagrel is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrova...
|
T0438 |
Proflavine Hemisulfate
|
1811-28-5
|
98%
|
|
Proflavine Hemisulfate is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used f...
|