LTR

LTR retrotransposons are class I transposable element characterized by the presence of Long Terminal Repeats (LTRs) directly flanking an internal coding region. As retrotransposons, they mobilize through reverse-transcription of their mRNA and integration of the newly created cDNA into another location. Their mechanism of retrotransposition is shared with retroviruses, with the difference that most LTR-retrotransposons do not form infectious particles that leave the cells and therefore only replicate inside their genome of origin.

Cat. No.	Product name	CAS No.	Purity
T15813	LY309887	127228-54-0	98%
T15813	LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.
T15002	CP-105696	158081-99-3	98%
T15002	CP-105696 is a selective antagonist of Leukotriene B4 Receptor (IC50: 8.42 nM).
T11487L	Fiboflapon sodium	1196070-26-4	98%
T11487L	Fiboflapon sodium (GSK2190915) is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of ...
T11487	Fiboflapon	936350-00-4	98%
T11487	Fiboflapon is an orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition...
T14210	Amelubant	346735-24-8	98%
T14210	Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315. Anti-inflammatory activity[1]. Amelubant (BIIL 284) is a potent, oral and long act...
T13295	Veliflapon	128253-31-6	98%
T13295	Veliflapon is an orally active and selective inhibitor of 5-lipoxygenase activating protein (FLAP). Veliflapon inhibits the synthesis of the leukotrienes B4 and ...
T16395	ONO4057	134578-96-4	98%
T16395	ONO4057 is an antagonist of the Leukotriene B4 receptor (IC50: 0.7±0.3 μM).
T15182	DW-1350	491577-61-8	98%
T15182	DW-1350 is an antagonist of LTB4 receptor.
TN5164	Trans-Hinokiresinol	17676-24-3	98%
TN5164	Hinokiresinol is a novel inhibitor of LTB4 binding to the human neutrophils, it has antiallergic effect, it inhibits IgE-induced mouse passive cutaneous anaphyla...
T17191	Bunaprolast	99107-52-5	98%
T17191	Bunaprolast shows significant inhibition of lipoxygenase and TXB2 release. Bunaprolast is a potent inhibitor of LTB4 production in human whole blood.
T68155	Tebufelone	112018-00-5	98%
T68155	Tebufelone is a potent in vitro inhibitor of CO , a novel non-steroidal anti-inflammatory drug (NSAID) belonging to the di-tert-butylphenol (DTBP) class that has...
T21504	γ-Linolenic Acid methyl ester	16326-32-2	98%
T21504	γ-Linolenic Acid methyl ester is a weak leukotriene B4 (LTB4) receptor antagonist.
T3738	3-(4-Hydroxyphenyl)-1-propanol	10210-17-0	98%
T3738	3-(4-hydroxyphenyl)-1-propanol is a member of the class of compounds known as 1-hydroxy-2-unsubstituted benzenoids.
T3148	MK-571 sodium	115103-85-0	98%
T3148	MK-571 is a selective, orally active antagonist of the CysLT1 receptor. MK571 is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the...
T22358	Etalocib	161172-51-6	98%
T22358	Etalocib is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotr...
T4192	Hnps-PLA Inhibitor	185298-58-2	98%
T4192	Hnps-PLA Inhibitor is an inhibitor of human nonpancreatic secretory Phospholipase A (hnps-PLA).
T11886	LTβR-IN-1	2189366-77-4	98%
T11886	LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor. LTβR-IN-1 has a selective inhibitory effect on the nuclear translocation of p52 of TNF12...
T68108L	Moxilubant HCl	146957-32-6	98%
T68108L	Moxilubant HCl is a small molecule leukotriene B4 receptor 1 (LTB4R) antagonist for the treatment of immune system disorders, skin and musculoskeletal disorders,...
T28974	Ticolubant	154413-61-3	98%
T28974	Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migrati...
T7841	MK 571	115104-28-4	98%
T7841	MK 571 is an orally active antagonist of CysLT1 receptor .