T8214 |
Kushenol E
|
99119-72-9
|
98%
|
|
Kushenol E is a class of flavonoids isolated from Sophora flavescens. It is a non-competitive IDO1 inhibitor (IC50: 7.7 μM, Ki: 9.5 μM), has anti-tumor activity....
|
T5S0053 |
Coptisine
|
3486-66-6
|
98%
|
|
1. Coptisine treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myoca...
|
T4307 |
PF-06840003
|
198474-05-4
|
98%
|
|
PF-06840003 is a specific and oral active IDO-1 inhibitor.
|
T4142 |
PCC0208009
|
1668565-74-9
|
98%
|
|
IDO-IN-2 is an IDO inhibitor extracted from patent WO/2015031295 A1, compound example 1.
|
T4532 |
Linrodostat
|
1923833-60-6
|
98%
|
|
BMS-986205 is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.
|
TQ0071 |
Navoximod
|
1402837-78-8
|
98%
|
|
Navoximod (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM).
|
T1847 |
Necrostatin-1
|
4311-88-0
|
98%
|
|
Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis (EC50: 490 nM in Jurkat cells).
|
T2718 |
Palmatine chloride
|
10605-02-4
|
98%
|
|
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
|
T11615 |
IDO-IN-12
|
1888341-29-4
|
98%
|
|
IDO-IN-12 is an inhibitor of indoleamine 2,3-dioxygenase (IDO).
|
T11616 |
IDO-IN-13
|
2291164-02-6
|
98%
|
|
IDO-IN-13 is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor (EC50: 17 nM).
|
T10199 |
GNF-PF-3777
|
77603-42-0
|
98%
|
|
GNF-PF-3777 (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2; Ki: 0.97 μM).
|
T5S0056 |
Coptisine chloride
|
6020-18-4
|
98%
|
|
1. Coptisine chloride can be absorbed across intestinal epithelial cells, and completely absorbed compounds.
|
T1806 |
IDO-IN-7
|
1402836-58-1
|
98%
|
|
NLG919 is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.
|
T7660 |
IDO inhibitor 1
|
1204669-37-3
|
98%
|
|
IDO inhibitor 1 is an potent inhibitor of indoleamine-2,3 dioxygenase (IDO) ( IC50 <100 nM).with potential immunomodulating and antineoplastic activities.
|
T6543 |
Indoximod
|
110117-83-4
|
98%
|
|
Indoximod is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades...
|
T39476 |
NLG802
|
2071683-99-1
|
98%
|
|
NLG802 is a prodrug of indoximod, an orally active indoleamine 2,3-dioxygenase (IDO) inhibitor.
|
T3548 |
Epacadostat
|
1204669-58-8
|
98%
|
|
Epacadostat is an oral-available inhibitor of indoleamine 2, 3-dioxygenase (IDO1), increasing the proliferation and activation of various immune cells and reduci...
|
T9164 |
BMS-986242
|
1923844-48-7
|
98%
|
|
BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.
|
T7181 |
IDO-IN-1
|
914638-30-5
|
98%
|
|
IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively...
|
T4S0051 |
Coptisine sulfate
|
1198398-71-8
|
98%
|
|
1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.
|