y15

Y15 (1,2,4,5-Benzenetetramine tetrahydrochlor) is a potent and specificsmall-molecule FAK scaffolding inhibitor that inhibits its autophosphorylation activity, blocks tumor growth.

AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].

XY153 (compound 8l) is a BD2-selective BET inhibitor that binds BRD4 BD2 with an IC50 of 0.79 nM, BRD3 BD2 with an IC50 of 5.31 nM, and BRD2 BD2 with an IC50 of 5.09 nM. XY153 is used to study acute myeloid leukaemia and cancer.

PY159 is a humanized antibody expressed in CHO cells, targeting TREM1 CD354. It features a human IgG1 heavy chain and a human κ light chain, with a predicted molecular weight (MW) of 143.66 kDa. For its isotype control, see Human IgG1 kappa, Isotype Control.

KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 μM, KGYY15 activates the NF-κB pathway by 33%.