tropane

L-Hyoscyamine (Daturine) functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as well as the eye, heart, bladder, and gastrointestinal tract. Hyoscyamine is a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. These inhibitory effects cause a decrease in saliva, bronchial mucus, gastric juices, and sweat. Furthermore, its inhibitory action on smooth muscle prevents bladder contraction and decreases gastrointestinal motility.

L-Hyoscyamine sulfate (Levsin Sulfate) is the sulfate salt of a belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. Hyoscyamine functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as well as the eye, heart, bladder, and gastrointestinal tract. These inhibitory effects cause a decrease in saliva, bronchial mucus, gastric juices, and sweat. Furthermore, its inhibitory action on smooth muscle prevents bladder contraction and decreases gastrointestinal motility.

N-Boc-exo-3-Aminotropane ,with CAS No. 744183-20-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N-Boc-exo-3-Aminotropane provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Endo-3-Boc-Aminotropane ,with CAS No. 132234-69-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Endo-3-Boc-Aminotropane provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2,6-Tropanediol is a useful organic compound for research related to life sciences and the catalog number is T124468.

3-Acetoxytropane is a useful organic compound for research related to life sciences and the catalog number is T125006.

AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) is an inhibitor of dopamine transporter (DAT) and dopamine uptake(IC50 = 71 nM).

Pseudotropine can cause hepatic necrosis and gastritis with ulceration or erosions.

Scopolamine hydrobromide is a tropane alkaloid derived from the Solanaceae family. It is a high-affinity (nanomolar level) muscarinic receptor antagonist and can also reversibly inhibit 5-HT₃ receptor responses (IC₅₀ = 2.09 μM). It is commonly used to induce animal models of Alzheimer's disease or memory impairment.

Littorine is a tropane alkaloid found in a variety of plants including Datura and Atropa belladonna. It is closely related in chemical structure to atropine, hyoscyamine, and scopolamine, which all share a common biosynthetic pathway.

Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50= <0.1 nM in a radioligand binding assay using isolated porcine brain membranes) and a derivative of atropine .1,2It reduces acetylcholine-induced decreases in blood pressure in rats when administered intravenously with an ED50value of 5.5 μg/kg.2Methylatropine reduces salivation, induces mydriasis, and increases heart rate in dogs.3 1.Schmeller, T., Sporer, F., Sauerwein, M., et al.Binding of tropane alkaloids to nicotinic and muscarinic acetylcholine receptorsPharmazie50(7)493-495(1995) 2.Brezenoff, H.E., Xiao, Y.-F., and Vargas, H.A comparison of the central and peripheral antimuscarinic effects of atropine and methylatropine injected systemically and into the cerebral ventriclesLife Sci.42(8)905-911(1988) 3.Albanus, L.Central and peripheral effects of anticholinergic compoundsActa Pharmacol. Toxicol. (Copenh)28(4)305-326(1970)

L-Hyoscyamine-d3-1 (Hyoscyamine-d3) is a deuterium-labeled variant of L-Hyoscyamine. L-Hyoscyamine (Daturine) is a naturally occurring tropane alkaloid found in plants and acts as an effective competitive antagonist of muscarinic receptors (MR). It is the levorotatory isomer of Atropine.

Pseudotropine (Standard) is a reference standard for research and analysis in studies involving Pseudotropine. Pseudotropine can cause hepatic necrosis and gastritis with ulceration or erosions.

Withania somnifera extract is derived from the roots and leaves of the South African ginseng (Withania somnifera) and contains various bioactive components, including withanolides (such as withanolide A, withanolide D, and withaferin A), withanosides (such as withanoside IV and withanoside VI), alkaloids (such as isopelletierine and anaferine), β-sitosterol, benzoic acid, and tropane alkaloids. It has been extensively studied for its benefits in stress management, alleviating anxiety, enhancing physical performance, and overall health improvement.

Apohyoscine is a natural tropane alkaloid that can be isolated from the Datura ferox plant. Apohyoscine exhibits high selectivity for muscarinic acetylcholine receptors (mAChR) and also binds to targets such as ACHE and ADRA2A. Apohyoscine can be used in research on Alzheimer's disease.

L-Hyoscyamine sulfate hydrate, a naturally occurring tropane alkaloid, acts as an effective competitive antagonist of muscarinic receptors (MR). It is the levorotary isomer of Atropine.

Norcocaethylene hydrochloride is a compound classified as a tropane metabolite.

3-p-FBT (hydrochloride) [also known as 3b-FBT (hydrochloride) and Fluorotropacocaine (hydrochloride)] is classified as a tropane alkaloid.