toxoplasmosis

Dapsone (Sulphadione) has activity against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae.

Acetylspiramycin (Spiramycin B) targets 50S ribosome to inhibit protein synthesis.

Atovaquone (Atavaquone) is a hydroxynaphthoquinone that has antimicrobial activity and is being used in antimalarial protocols.

Azithromycin hydrate (CP-62993 dihydrate) is a semi-synthetic macrolide antibiotic structurally related to ERYTHROMYCIN. It has been used in the treatment of Mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.

Sulfadiazine sodium (Sulfadiazin-natrium) is a sodium salt form of sulfadiazine, an intermediate-acting bacteriostatic, synthetic sulfanilamide derivative.

Sulfadiazine (Sulphadiazine) is a synthetic pyrimidinyl sulfonamide derivative, short-acting bacteriostatic Sulfadiazine inhibits bacterial folic acid synthesis by competing with para-aminobenzoic acid. It is used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor, suppressing the growth of T. gondii strains with a TgDHFR IC50 of 1.57 ± 0.11 nM, a hDHFR IC50 of 308 ± 71 nM, and a hDHFR to TgDHFR selectivity ratio of 196.

Sulfadiazine D4 is a deuterium labeled Sulfadiazine. Sulfadiazine used for the treatment of toxoplasmosis.

ELQ316 is an antiparasitic compound. In mouse models of acute and latent toxoplasmosis, ELQ316 demonstrates high efficacy, with its in vitro IC50 values at the picomolar level.

Atovaquone D4 is the deuterium-labeled Atovaquone. Atovaquone is a medication used to treat or prevent pneumocystis babesia, malaria, toxoplasmosis, and pneumonia.