tetrandrine

Tetrandrine (Sinomenine A) is a naturally occurring biphenylisoquinoline alkaloid, a calcium channel inhibitor. Tetrandrine inhibits voltage-gated calcium channels (ICa) and Ca2+-activated potassium channels.

Tetrandrine 2'-N-β-oxide (Saponin YSM4) is a bis-benzylisoquinoline alkaloid with antihyperglycemic properties. At a dose of 1 mg/kg, it can reduce hyperglycemia in Streptozotocin-induced diabetic mice to about 50% of the original level. This compound is primarily studied for its potential in treating type 2 diabetes. Tetrandrine 2'-N-β-oxide can be isolated from Stephania tetrandra.

Tetrandrine 2'-N-α-oxide (compound 13) is a bisbenzylisoquinoline alkaloid with anti-inflammatory properties, isolated from the roots of Stephania tetrandra. It is applicable in research related to inflammation-related diseases.

Tetrandrine (Standard) is a reference standard for research and analysis in studies involving Tetrandrine. Tetrandrine (Sinomenine A) is a naturally occurring biphenylisoquinoline alkaloid, a calcium channel inhibitor. Tetrandrine inhibits voltage-gated calcium channels (ICa) and Ca2+-activated potassium channels.

Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.

(R)-Fangchinoline ((+)-Thalrugosine) is extracted from Stephania tetrandra S. Moore.

Bromotetrandrine is an P-glycoprotein inhibitor, which were developed and coadministered with chemotherapeutic drugs to overcome the effect of efflux pumps thus enhancing the chemosensitivity of therapeutics.

Isotetrandrine is a small molecule inhibitor, on various aspects of LPS-induced inflammation in vitro and in vivo. It dose-dependently suppresses the severity of LPS-induced ALI by inactivation of MAPK and NF-κB, which may involve the inhibition of tissue

Isotetrandrine N-2'-oxide is a natural product for research related to life sciences. The catalog number is TN4335 and the CAS number is 70191-83-2.

OY-101, an orally active compound, serves as a potent and specific inhibitor of P-glycoprotein (P-gp). It has the capability to sensitize drug-resistant tumors and counteract tumor multidrug resistance efficiently. Compared to Tetrandrine [1], OY-101 demonstrates enhanced water-solubility, cytotoxicity, and reversal activity.

Fangchinoline (Standard) is a reference standard for research and analysis in studies involving Fangchinoline. Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.