tetrahydrofolic acid

Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism.

(6S)-Tetrahydrofolic acid has 1000 times greater activity in promoting the binding of fluorodeoxyuridine monophosphate with thymidylate synthase compared to the (6R) form and exhibits 600 times higher activity as a growth factor for brewer's yeast (P. cerevisiae). It also has low affinity and high dissociation rates from folate-binding proteins.

5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivative of tetrahydrofolate, serving as the predominant natural dietary folate and the principal form of folate found in plasma and cerebrospinal fluid.

Tetrahydrofolic acid trihydrochloride (L-5,6,7,8-Tetrahydrofolic acid trihydrochloride) is a biologically active vitamin B9 derivative, a receptor for free formaldehyde, and an effective suicide substrate for mushroom tyrosinase, inhibiting indole ethylamine methylation by methyl-tetrahydrofolate.

Tetrahydrofolic acid (Standard) is a reference standard for research and analysis in studies involving Tetrahydrofolic acid. Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism.

(6S)-5,6,7,8-Tetrahydrofolic Acid Trihydrochloride (Standard) is a reference standard of (6S)-5,6,7,8-Tetrahydrofolic Acid Trihydrochloride intended for quantitative analysis, quality control, and related biochemical research applications.

Levomefolic Acid (Standard) is a reference standard for research and analysis in studies involving Levomefolic Acid. Levomefolic Acid (5-MTHF) is a natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. Levomefolinic acid is used as a treatment and to prevent Folate Deficiency

5-Methyltetrahydrofolic acid (Standard) is a reference standard for research and analysis in studies involving 5-Methyltetrahydrofolic acid. 5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivate of tetrahydrofolate. It is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid.

5-Methyltetrahydrofolic Acid-[13C5] Calcium Salt (Standard) is a reference standard of 5-Methyltetrahydrofolic Acid-[13C5] Calcium Salt intended for quantitative analysis, quality control, and related biochemical research applications.

10-FTHF is a donor of formyl groups in anabolism used as a substrate in formyltransferase reactions, which is important in purine biosynthesis.This compound is unstable in powder form and other related salt forms are recommended.

Anhydroleucovorin is the predominant, biologically active form of vitamin B9 (folate) that is utilized by the body for a multitude of vital cellular functions, including DNA synthesis, repair, and methylation, as well as the production of key neurotransmitters; Anhydroleucovorin plays an essential metabolic role in the remethylation pathway, converting the amino acid homocysteine to methionine, and serves as the main folate form found in systemic circulation and transported into tissues for physiological use.

10 FTHF disodium (10-Formyltetrahydrofolic acid disodium) is a form of tetrahydrofolate, a formyl donor in anabolism, involved in the synthesis of purine compounds.

Dihydrofolic acid (7,8-Dihydrofolic acid) is a folic acid derivative that produces tetrahydrofolic acid in the presence of dihydrofolic acid reductase.

N-(4-Aminobenzoyl)-L-glutamic acid is an oxidation product and a metabolite of tetrahydrofolate.1Levels of N-(4-aminobenzoyl)-L-glutamic acid are increased in the plasma of mice fed a high folic acid-containing diet.2 1.Reed, L.S., and Archer, M.C.Oxidation of tetrahydrofolic acid by airJ. Agric. Food Chem.28(4)801-805(1980) 2.Burton, M.A., Antoun, E., Penailillo, R.S., et al.Folic acid induces intake-related changes in the mammary tissue transcriptome of C57BL/6 miceNutrients12(9)2821(2020)

Aditoprime (Aditoprim) is a selective inhibitor of bacterial dihydrofolate reductase (DHFR) that exhibits potent enzymatic inhibition with IC50 values of 47 nM for Escherichia coli DHFR and 520 nM for Lactobacillus casei DHFR, Aditoprime functions by blocking the conversion of dihydrofolic acid to tetrahydrofolic acid.Aditoprime also demonstrate broad-spectrum antibacterial activity combined with favorable pharmacokinetic properties that support its use in antimicrobial research and drug development studies.

Aminopterin (4-Aminofolic acid) is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase

Dihydrofolic acid (Standard) is a reference standard for research and analysis in studies involving Dihydrofolic acid. Dihydrofolic acid (7,8-Dihydrofolic acid) is a folic acid derivative that produces tetrahydrofolic acid in the presence of dihydrofolic acid reductase.