sulforaphane

Sulforaphane is a natural isothiocyanate that activates Nrf2 and inhibits AMPK-dependent signaling. Sulforaphane has antitumor and anti-inflammatory activities by increasing the transcription of tumor suppressor proteins and inhibiting histone deacetylase activity.

(R)-Sulforaphane (L-Sulforaphane) is a potent inducer of the Keap1/Nrf2/ARE pathway.

Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane.

Erysolin is a natural product with anti-cancer potential. It is cytotoxic to a variety of cancer cells (DU145, HCT 116, MCF7, HEP3B, SKOV3, SF-268) and has antibacterial activity against Escherichia coli.

Gluconapin potassium, a precursor to the potent anti-cancer isothiocyanate sulforaphane [1], serves as an important chemical compound in chemopreventive applications.

Glucoraphanin, the precursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, has antioxidant activity.