sn-1

SN-1 is a zinc chelator which increases steady-state expression level of A3G in the presence of Vif.

1-Docosahexaenoyl-sn-glycero-3-phosphocholine, an ester product, is a phospholipid containing DHA (docosahexaenoic acid), often used in biomedical research as an important source of omega-3 fatty acids.

1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine is an endogenous metabolite. 1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine is a non-limiting exemplary phosphatidyl choline.

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine is an endogenous metabolite identified in the aging mouse brain.

1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine is an endogenous metabolite.

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) is a phospholipid commonly found in cell membranes, with cholesterol compositions ranging from 0 to 60 mol%.

1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).

1-Myristoyl-2-hydroxy-sn-glycero-3-phosphate sodium is a salt form compound.1-Myristoyl-2-hydroxy-sn-glycero-3-phosphate is a lipid and endogenous metabolite related to LPA (lysophosphatidic acid).

1-Stearoyl-sn-glycerol 3-phosphate sodium, a biologically active phospholipid, plays a crucial role in regulating cell motility, proliferation, invasion, survival, and the production of growth factors through interactions with G protein-coupled receptors (GPCR). Synthesized during the formation of membrane phospholipids, this compound typically has a low plasma concentration (approximately 100nM) and originates from various cell types, including activated platelets, epithelial cells, leukocytes, neuronal cells, and tumor cells. Its distinctive structure features stearic acid at the sn-1 position and a hydroxyl group at the sn-2 position.

1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE (18:0p/22:6-PE) is a lipid identified in rat brain tissue using mass spectrometry imaging techniques. It exhibits specific structural and distribution properties, allowing the differentiation of isomers of various fatty acid chains through refined methods.

1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound utilized in the preparation of liposomes. Liposomes, forming the central component of concentric phospholipid bilayer vesicles, are pivotal in constructing drug delivery systems for anti-cancer and anti-infection applications. They effectively encapsulate hydrophilic payloads within their aqueous internal spaces, while lipophilic compounds are integrated into and become part of the lipid bilayer. This compound is particularly effective for delivering antisense oligonucleotides, addressing challenges such as inefficient cellular uptake and rapid loss in the body.

1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC (13-HODE-PC) is an oxidized phospholipid with Palmitic acid at the sn-1 position and 13(S)-HODE at the sn-2 position. This compound can compete with 125I-NO2-LDL (5 g/ml) for binding to CD36-transfected 293 cells, with an IC50 value exceeding 200 μM.

1-Myristoyl-2-Linoleoyl-sn-glycero-3-PC is a phospholipid identified in human plasma, characterized by the presence of Myristic acid and Linoleic acid at the sn-1 and sn-2 positions, respectively.

1-Oleoyl-sn-glycero-2,3-cyclic-phosphate ammonium (18:1 Cyclic LPA) is a cyclic lysophosphatidic acid used in lipid vesicle (liposome) formation.

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4'-bisphosphate) ammonium can modulate the activity of the actin network associated with endocytosis.

1-Palmitoyl-2-oleoyl-sn-glycerol,1-Oleoyl-3-palmitoylglycerol (1:1) is a 1:1 mixture of 1-Palmitoyl-2-oleoyl-sn-glycerol and 1-Oleoyl-3-palmitoylglycerol. This compound represents a primary active component of diacylglycerol (DAG) and functions as a hypoxia-inducible factor (HIF) inducer.

1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA is a phospholipid that contains arachidonic acid at the sn-1 position, serving as a precursor to 1-Monoarachidin. It binds with the LPA2/EDG4 receptor and can inhibit the secretion of TNF-α and IL-6 induced by LPS in wild-type dendritic cells but does not affect Lpa2-/- dendritic cells. Additionally, it reduces the differentiation of HT-29 human colon cancer cells into goblet cells in the presence of sodium butyrate.

1-Palmitoyl-2-10-pahsa-3-oleoyl-sn-glycerol (16:0-10-Pahsa-18:1-TG) is a triglyceride composed of fatty acid esters including Palmitic acid, hydroxy fatty acid (FAHFA) 10-PAHSA, and Oleic acid.

1-Myristyl-2-hydroxy-sn-glycero-3-PA (1-Myristyl LPA) is a derivative of lysophosphatidic acid. In HEL cells, 1-Myristyl-2-hydroxy-sn-glycero-3-PA can elevate intracellular calcium levels.

1-Arachidonoyl-2-hydroxy-sn-glycero-3-PA (sodium) [1-Arachidonoyl-sn-glycerol 3-phosphate (sodium)] is a phospholipid containing arachidonic acid at the sn-1 position. It binds to the LPA2/EDG4 receptor with an EC50 of 10 nM and is present in the rat brain, representing 37% of arachidonic acid lysophosphatidic acid species. This compound serves as a precursor to 1-arachidonoyl-sn-glycerol and inhibits the secretion of TNF-α and IL-6 from dendritic cells stimulated by wild-type LPS. Additionally, 1-arachidonoyl-2-hydroxy-sn-glycero-3-PA (sodium) can suppress the differentiation of HT-29 colon cancer cells into goblet cells in the presence of sodium butyrate.

1-(1(Z)-Hexadecenyl)-2-linoleoyl-sn-glycero-3-phosphocholine is a plasmalogen characterized by the presence of 1(Z)-hexadecenoic acid and linoleic acid at the sn-1 and sn-2 positions, respectively. It counteracts lead-induced reductions in cell viability and suppresses increases in reactive oxygen species (ROS) and oxidized phospholipids in HepG2 hepatocytes. In dogs with myxomatous mitral valve disease, serum levels of this compound decrease when their diet is enriched with medium chain triglycerides, fish oil, carnitine precursors, magnesium, and antioxidants.

1-Dodecanoyl-sn-glycerophosphoethanolamine is a bioactive cehmical.

1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid and endogenous metabolite used in biochemical experiments and drug synthesis research.

1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity.