sdf-1α-cxcr4

FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hiv activity.

Alx40-4C trifluoroacetate is a chemokine receptor (CXCR4) inhibitor, which inhibits the binding of sdf-1 to CXCR4.Alx40-4ctrifluoroacetate was also an APJ receptor antagonist with an IC50 value of 2.9 M.

ALX40-4C is a small peptide inhibitor of the chemokine receptor CXCR4 that can inhibit X4 strains of HIV-1.

LY2510924 is an effective and selective CXCR4 antagonist. It blocks SDF-1 binding to CXCR4 (IC50: 0.079 nM).

CTCE-0214, a chemokine CXC receptor 4 (CXCR4) agonist and SDF-1α (stromal cell-derived factor-1α) peptide analog, exhibits anti-inflammatory properties. It is applicable in the research of inflammation, sepsis, and systemic inflammatory syndromes [1] [2] [3].

SDF-1α (human) serves as a chemotactic agent for mononuclear cells through its interaction with the CXCR4 receptor, facilitating critical biological processes such as stem cell homing, retention, survival, and proliferation, in addition to cardiomyocyte repair, angiogenesis, and ventricular remodeling post-myocardial infarction. It holds significant utility in cardiovascular disease research [1] [2].