salannin

Salannin is a limonoid from Azadirachta indica A. Juss.

3-Deacetyl-4-demethylsalannin is a type of salannin limonoid and functions as an anticancer agent. It induces cytotoxic activity against leukemia and gastric cancer cells, while showing no activity at concentrations up to 100 μM against lung and breast cancer cells. It is useful in research on leukemia and gastric cancer.

3-O-Deacetyl-3-O-tigloylsalannin is a limonoid of the salannin class and a cytotoxic agent found in neem fruits. [3-O-Deacetyl-3-O-tigloylsalannin] is applicable in research related to leukemia, gastric cancer, and breast cancer.

Deacetylsalannin shows antifeedant activity against Reticulitermes speratus Kolbe (95% protective concentration or PC95 = 1373.1 ug/disc).

21-Hydroxyisoohchininolide is a salannin-type limonoid that inhibits nitric oxide production in LPS-induced mouse macrophages. It exhibits cytotoxic activity against leukemia and breast cancer cells. Additionally, 21-Hydroxyisoohchininolide suppresses Epstein-Barr virus early antigen activation in lymphocytes induced by Phorbol 12-myristate 13-acetate (TPA). It is applicable in the study of leukemia, breast cancer, and infectious diseases.