s 101

S101 is an inhibitor of proliferating T-cells, rescuing mice from superantigen-induced shock.

EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.

Navoximod phosphate is an indoleamine 2,3-dioxygenase (IDO) inhibitor, immunomodulator and antineoplastic.

(S)-OY-101 serves as the isomer of OY-101.

KHS101 is a novel inhibitor of transforming acidic coiled-coil protein 3 (TACC3). It is a selective inducer of neuronal differentiation.

LAS101057 is a novel orally available and potent and selective A2B receptor antagonist for the study of asthma.

Sodium dodecylbenzenesulfonate (Bio-Soft S 101 sodium) is a non-ionic surfactant frequently used in cleaning and maintaining industrial equipment. It demonstrates strong cleaning properties and environmental compatibility, effectively removing oil, dirt, and other contaminants. Moreover, this compound finds application in the textile, paper, and leather industries for dye fixing and stabilization. While it is not directly used in the medical field, it plays a significant role in industrial and laboratory research.

ADS1017 is an antagonist of histamine receptor (histamine receptor) and muscarinic receptor (muscarinic receptor), displaying strong affinity for hH3R, hH4R, hM2R, and hM4R with pKi values of 6.8, 5.5, 7.4, and 7.2, respectively. In mouse models of pain induced by Capsaicin or Oxaliplatin, ADS1017 exhibits analgesic and anti-hyperalgesic effects.

KHS101 is a TACC3 inhibitor and can selectively induce a neuronal differentiation phenotype.

Lorundrostat (MT-4129) is an aldosterone synthase inhibitor with antihypertensive activity that lowers systolic blood pressure.

3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6'-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione is a useful organic compound for research related to life sciences. The catalog number is T67236 and the CAS number is 1352957-59-5.

Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.

EVT-101, also known as ENS-101, is an experimental medication which originated from Roche and is under development by Evotec AG for the treatment of major depressive disorder. It acts as a selective NMDA receptor subunit 2B (NR2B) antagonist.

Foslevcromakalim (QLS-101) is an adenosine triphosphate-sensitive potassium channel (KATP) opener that is converted to its active form by alkaline phosphatase in vivo. It reduces intraocular pressure in normotensive mice and is suitable for glaucoma research.

Fluzoparib (SHR3162) is a novel, potent, and orally available inhibitor of PARP, potentially for the treatment of solid tumours.

INBRX-105 is a recombinant humanized bispecific antibody that targets programmed death-ligand 1 (PD-L1) and 4-1BB (CD137), exhibiting potential checkpoint inhibition, immune stimulation, and anti-tumor activity. By binding to 4-1BB on activated T-lymphocytes and PD-L1 on tumor cells, INBRX-105 enhances T-cell co-stimulation and inhibits PD-L1-mediated T-cell suppression, potentially reducing tumor growth. It demonstrates anti-tumor efficacy and increased T-cell frequency in patients with solid tumors and in vivo. Molecular weight: 101.9 kD.

AV-101 (4-Cl-KYN) , a prodrug antagonist at the glycine site of the NMDA receptor, has antidepressant activity and reduces levodopa-induced dyskinesia in MPTP monkeys.

E3LigaseLigand-linker Conjugate 101 is a conjugate consisting of an E3 ligase ligand and a linker, specifically made up of (S,R,S)-AHPC and a corresponding linker. (S,R,S)-AHPC is a von Hippel-Lindau (VHL) ligand based on VH032, capable of recruiting VHL protein. This conjugate is a crucial intermediate for synthesizing complete PROTACs molecules.