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(1)
By Target- NF-κB
- Nrf2(1)
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Results for "
rta dh 404
" in TargetMol Product Catalog- Inhibitors & Agonists1
CDDO-dhTFEA 
T136041191265-33-4
CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expression of related genes, attenuates NF-κB and transforming growth factor-β pathway activation, and mitigates glomerulosclerosis, interstitial fibrosis, and inflammation in rats with chronic kidney disease (CKD).
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