rodents — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4542	Clonixin	Clonixic acid	Others
	Clonixin (Clonixic acid) is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. This compound has been reported to block prostaglandin synthesis, and to block inward calcium currents.		Others
T16240	N,N'-Diacetyl-L-cystine	(Ac-Cys-OH)2,DiNAC	Others
	N,N'-Diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL...		Others
T5573	Coenzyme Q9	Ubiquinone Q9,Ubiquinone 9,CoQ9	Apoptosis , Endogenous Metabolite
	Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma. CoQ9 in human plasma may originate as a product of incomplete CoQ10 biosynthesis or from the diet.		Apoptosis , Endogenous Metabolite
T24121	GW438014A	GW 438014 A,GW-438014-A	Neuropeptide Y Receptor
	GW438014A is a potent, selective antagonist of the NPY-Y5 receptor, effectively inhibiting food consumption and curbing body weight gain in obese rodents.		Neuropeptide Y Receptor
T28531	Facinicline hydrochloride	RG3487	5-HT Receptor , AChR
	Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM). Facinicline hydrochloride improves cognition and sensorimot...		5-HT Receptor , AChR
T60221	Tabernanthalog	TBG	5-HT Receptor
	Tabernanthalog (TBG) is a 5-HT2A agonist. In rodents,Tabernanthalog has been found to promote structural neuroplasticity, reduce alcohol-seeking and heroin-seeking behavior, and produce antidepressant effects.		5-HT Receptor
T21380	Pravadoline	WIN 48098-6,WIN48098-6,WIN-48098-6	Cannabinoid Receptor
	Pravadoline (WIN48098-6) is a cannabinoid receptor agonist. Pravadoline inhibited the PGs synthesis in mouse brain and displayed antinociceptive activity in rodents subjected to a variety of thermal, chemical, and mechan...		Cannabinoid Receptor
T21556	Hydroxytacrine maleate	Velnacrine maleate,HP 029 maleate	AChE
	Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase (cholinesterase) inhibitor that enhances memory in rodents and may be used in the study of Alzheimer's dementia of the Alzheimer type (SDAT).		AChE
T13318	VU0650786		GluR
	VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with antidepressant and anxiolytic activity in rodents.		GluR
T4351	DAMGO	Dagol,DAGO,RX-783006	Opioid Receptor
	DAMGO (DAGO) is an opioid receptor agonist with the ability to affect the locomotive activity in rodents. Possible analgesic agent due to μ-opiod receptor interaction.		Opioid Receptor
T8862	ML 254		GluR
	ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinas...		GluR
T8141	L-Cysteine hydrochloride	L-Cysteine HCl	Others , Endogenous Metabolite
	L-Cysteine hydrochloride (L-Cysteine HCl) is a conditionally essential amino acid,L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents and humans		Others , Endogenous Metabolite
T7720	CGP 37849	CGP-37849,CGP37849	NMDAR , iGluR
	CGP 37849 is a competitive orally active N-methyl-D-aspartate (NMDA) receptor antagonist ((Ki = 35 nM)) with potency.CGP 37849 is an anticonvulsant in rodents and also has antidepressant and anxiolytic properties.		NMDAR , iGluR
T25672	Lesopitron		5-HT Receptor
	Lesopitron is an anxiolytic with pre- and postsynaptic 5-HT1A agonist activity and is more effective than 5-HT1A agonists in rat social interaction and marmoset anxiety models. lesopitron counteracts benzodiazepine withd...		5-HT Receptor
TN5283	L-Cysteine hydrochloride hydrate	L-Cysteine hydrochloride monohydrate	Others , Endogenous Metabolite
	L-Cysteine hydrochloride hydrate (L-Cysteine hydrochloride monohydrate) is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), taurine and gl...		Others , Endogenous Metabolite
T16816	S 18986		GluR
	S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in rodents. It induces the release of noradrenaline and acetylcholine...		GluR
T1208	Citicoline sodium	Citicoline sodium salt,CDP-choline	Apoptosis , Others , Endogenous Metabolite
	Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demons...		Apoptosis , Others , Endogenous Metabolite
T8720	PRX-07034 hydrochloride	PRX-07034	5-HT Receptor
	PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a poten...		5-HT Receptor
T67955	Ensaculin	Anseculin
	Ensaculin (Anseculin), a novel benzopyrone partially substituted with piperazine, showed memory-enhancing effects in passive and conditioned avoidance paradigms in normal and artificially amnesic rodents. It showed neuro...
TF0106	Cholesteryl Hemisuccinate Tris Salt		Apoptosis
	Cholesteryl Hemisuccinate Tris Salt is an acidic cholesteryl ester with hepatoprotective and anticancer activity.Cholesteryl hemisuccinate is a membrane stabilizer in dipalmitoylphosphatidylcholine liposomes containing C...		Apoptosis