rrna — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3532	5S rRNA modificator	FAI,Furoyl Acylimidazole	Others
	5S rRNA modificator (FAI), used in 5S rRNA RNA modification, is a suitable electrophile for 2'-hydroxyl acylation on structured RNA molecules.		Others
T8643	NAI	5S rRNA modificator 2	Others
	NAI (5S rRNA modificator 2) is an RNA SHAPE reagent.		Others
T13499	3-Methyluridine		Endogenous Metabolite
	3-Methyluridine is a modified nucleoside of cellular RNA.		Endogenous Metabolite
T9726	2’-OMe-Guanosine		Apoptosis , Nucleoside Antimetabolite/Analog
	2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.		Apoptosis , Nucleoside Antimetabolite/Analog
T35648	4-Thiouridine		Others
	4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directl...		Others
T16698	Pyronin Y	C.I. 45005,Pyronine G	Others
	Pyronin Y (Pyronine G) is an intercalating cationic dye that shows specificity towards RNA.		Others
T4S0554	Theaflavine-3,3'-digallate	TFBG,theaflavin digallate	Others
	1. Theaflavine-3,3'-digallate (theaflavin digallate) and lactic acid together could reduce herpes simplex virus transmission.		Others
T2100	CX-5461		DNA/RNA Synthesis
	CX-5461, a selective inhibitor of rRNA synthesis, suppresses Pol I-driven transcription of rRNA.		DNA/RNA Synthesis
TN7106	2′-O-Methyluridine		Others
	2′-O-Methyluridine is a natural product that found in RNA such as rRNA, snRNA, snoRNA and tRNA in Archaea, Bacteria, and Eukaryota.		Others
T22297	Clindamycin hydrochloride monohydrate	Clindamycin alcoholate	Antibiotic
	Clindamycin hydrochloride monohydrate (Clindamycin alcoholate) is a protein synthesis inhibitor used orally, capable of diminishing virulence factor expression in Staphylococcus aureus at sub-minimum inhibitory concentra...		Antibiotic
T1349	5-Fluorouridine		Others , DNA/RNA Synthesis
	5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound...		Others , DNA/RNA Synthesis
T10067	2',5-Difluoro-2'-deoxycytidine		HCV Protease
	2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.		HCV Protease
T1707	EA25		Others
	EA25 has been identified in the clone library of the bacterial 16S rRNA gene sequence.		Others
T61121	NusB-IN-1
	NusB-IN-1 (Compound 22r) is a highly effective bacterial rRNA synthesis inhibitor, administered orally. It exhibits potent antimicrobial activity against MRSA and VRSA [1].
T64150	CX-5461 dihydrochloride
	CX-5461 dihydrochloride is a potent, orally active inhibitor of Pol I-mediated rRNA synthesis that acts on HCT-116 cells (IC50: 142 nM), A375 cells (IC50: 113 nM) and MIA PaCa-2 cells (IC50: 54 nM), and to a lesser exten...
T27165	Diazaborine	Diazaborine compound 2b18,Pkf 84.474,Pkf 84474,Pkf-84474,SA-84474
	Diazaborine inhibits maturation of rRNAs for the large ribosomal subunit. Diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1. Diazaborine treatment causes, within minutes, a rapid redistribution of ...
T69908	Pidnarulex HCl
	Pidnarulex HCl is the salt form of CX-5461, a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage. CX-5461 selectively inhi...
T79015	SEQ-9
	SEQ-9 is an orally active inhibitor targeting the Mycobacterium tuberculosis (Mtb) 23S bacterial ribosome, demonstrating an inhibitory concentration (IC50) around 170 nM against unmethylated Mtb ribosomes and showing pot...
T37154	7-Methylguanosine 5'-diphosphate sodium
	7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, is utilized in the synthesis of mRNA cap analogues[1].