r-1415

Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.

DSR-141562 is a new compound that can be taken orally and has a specific ability to inhibit phosphodiesterase 1 (PDE1) in the brain. This compound exhibits a preference for inhibiting human PDE1B, with an IC50 value of 43.9 nM. It also shows moderate inhibition of human PDE1A (IC50 = 97.6 nM) and PDE1C (IC50 = 431.8 nM). DSR-141562 is particularly useful in the study of positive symptoms, negative symptoms, and cognitive impairments associated with schizophrenia.

Methyl 2-aminothiophene-3-carboxylate ,with CAS No. 4651-81-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Methyl 2-aminothiophene-3-carboxylate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-Methyl-2-pyridone ,with CAS No. 1003-56-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Methyl-2-pyridone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-Amino-3-methylisoxazole ,with CAS No. 14678-02-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Amino-3-methylisoxazole provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Methyl o-toluate ,with CAS No. 89-71-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Methyl o-toluate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2,3-Dihydrobenzo[b]furan-5-carboxylic acid ,with CAS No. 76429-73-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2,3-Dihydrobenzo[b]furan-5-carboxylic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4-Fluorobenzylurea ,with CAS No. 76523-24-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Fluorobenzylurea provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

6-Ethynylquinoxaline ,with CAS No. 442517-33-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 6-Ethynylquinoxaline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

SR14150 is a partial agonist of high-affinity NOP receptor.