promazine

Promazine hydrochloride (Romtiazin hydrochloride) is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.

ProMazine-D6 hydrochloride is a deuterated compound of ProMazine hydrochloride. ProMazine hydrochloride (T0766) has a CAS number of 53-60-1. Promazine hydrochloride is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.

Promazine hydrochloride (Standard) is the standard substance of Promazine hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Promazine hydrochloride (Romtiazin hydrochloride) is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as an antiemetic.

Triflupromazine hydrochloride (Fluopromazine hydrochloride), an antipsychotic medication, is Dopamine D1/D2 receptor antagonists.

Desmonomethylpromazine is a demethylated metabolite of Promazine that can penetrate the brain. It enters red blood cells and tissues via passive diffusion and is distributed in organs such as the lungs, liver, and kidneys in rats.

Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in the central nervous system (CNS) and promotes LDHA-mediated AMBRA1 ubiquitination, used for treating mental disorders, sedation, and antiemesis.

Levomepromazine (Methotrimeprazine) is an orally active aliphatic phenothiazine antipsychotic compound and a Ca2+ release inducer, exhibiting antiviral, anti-inflammatory, neuroprotective, analgesic, and anti-nociceptive activities. Levomepromazine inhibits dopaminergic, cholinergic, serotoninergic, and histaminergic receptors, and is used for research in neurodegenerative diseases.

7-Hydroxychlorpromazine, an active metabolite of Chlorpromazine, can reversibly counteract the suppression of regionally dense dopaminergic neurons induced by Amphetamine.

Acepromazine-1-Piperazinepropanamine (compound 10) is an E3 ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugate) consisting of a cereblon ligand and a linker. This compound can target protein ligands to form the PROTAC molecule, TrimTAC1.

Acepromazine-OTs is a cereblon (CRBN) ligand designed for recruiting CRBN protein. It can be linked through a linker to a target protein ligand to form a PROTAC molecule, TrimTAC1.

8-Hydroxychlorpromazine is a metabolite of Chlorpromazine that can enhance the hyperglycemic response following glucose loading, suggesting a possible synergistic role in Chlorpromazine-induced glucose metabolism disorders. It holds potential for research into metabolic diseases.

Acepromazine-1-piperazinepropanamine dihydrochloride (compound 10) is an E3 ligase ligand-linker conjugate, incorporating a TRIM21 ligand and a linker. It can bind to target protein ligands, forming the PROTAC molecule known as TrimTAC1.

7-hydroxy Chlorpromazine is an active metabolite of the typical antipsychotic chlorpromazine .1In vivo, 7-hydroxy chlorpromazine (5 mg/kg) increases plasma prolactin levels in male rats. It also reverses D-amphetamine-induced depression of the dopaminergic neuronal firing rate in the rat substantia nigra in rats when administered at a dose of 1.6 mg/kg.2 1.Meltzer, H.Y., Fang, V.S., Simonovich, M., et al.Effect of metabolites of chlorpromazine on plasma prolactin levels in male ratsEur. J. Pharmacol.41(4)431-436(1977) 2.Bunney, B.S., and Aghajanian, G.K.A comparison of the effects of chlorpromazine, 7-hydroxychlorpromazine and chlorpromazine sulfoxide on the activity of central dopaminergic neuronsLife Sci.15(2)309-318(1974)

Opromazine hydrochloride belongs to the phenothiazine class of antipsychotics and reduces the activity of dopaminergic pathways by blocking dopamine receptors in the brain. It is mainly used for the treatment of psychiatric disorders such as schizophrenia and psychosis.

(±)-Levomepromazine（(±)-Methotrimeprazine） is the racemate of Levomepromazine, an orally administered, low-potency phenothiazine antipsychotic that acts by blocking a variety of receptors, including adrenergic, dopamine, histamine, muscarinic acetylcholine and serotonin receptors.

Chlorpromazine Sulfone Hydrochloride is a metabolite of Chlorpromazine -- an anti-emetic and anti-psychotic agent. It may also be used as a potential N-methyltransferase inhibitor.

Levomepromazine HCl is a phenothiazine with pharmacological activity similar to that of both CHLORPROMAZINE and PROMETHAZINE. It has the histamine-antagonist properties of the antihistamines together with CENTRAL NERVOUS SYSTEM effects resembling those of chlorpromazine.

Levomepromazine Maleate is a Tricyclic antidepressant (TCA), acting as a serotonin–norepinephrine reuptake inhibitor (SNRI) and also having other activities including antihistamine, antiadrenergic, antiserotonergic, anticholinergic, and sodium channel-blocking effects.

ACEPROMAZINE MALEATE is a dopamine receptor antagonist

Propionylpromazine hydrochloride (Propiopromazine hydrochloride) is a dopamine receptor D2 (DRD2) antagonist.

(±)-Levomepromazine-D6 is a deuterated compound of  (±)-Levomepromazine (T60944). Methotrimeprazine (Racemic) has a CAS number of 851-68-3.

Acepromazine-D6 maleate is a deuterated compound of Acepromazine maleate. Acepromazine maleate (T7728) has a CAS number of 3598-37-6. ACEPROMAZINE MALEATE is a dopamine receptor antagonist

Levomepromazine-d6 hydrochloride (Methotrimeprazine-d6 hydrochloride) is the deuterium-labeled derivative of Levomepromazine hydrochloride. Levomepromazine (Methotrimeprazine) hydrochloride is an orally active antipsychotic compound that also induces Ca2+ release. It inhibits the SERCA pump, leading to elevated cytosolic Ca2+ levels, and antagonizes multiple neurotransmitter receptors, including dopaminergic, cholinergic, serotonin, and histamine receptors. Additionally, Levomepromazine hydrochloride induces adaptive endoplasmic reticulum stress and autophagy (autophagy), while also exhibiting antiviral, anti-inflammatory, neuroprotective, analgesic, and anti-nociceptive properties. It is utilized in the study of psychiatric disorders and the alleviation of nausea and vomiting.

Levomepromazine sulfoxide-d3 (Methotrimeprazine sulfoxide-d3) is a deuterium-labeled version of Levomepromazine sulfoxide.