pgf2a

Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.

11-deoxy-PGF2a is a thromboxane A2 receptor agonist that partially alleviates crowding in Lpar3(−/−) female embryos and induces smooth muscle contraction in the aorta, vena cava, and trachea.

Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor. It has a relative potency of 756% compared to PGF2α for binding to the FP receptor on ovine luteal cells.

Carboprost (15(S)-15-Methyl Prostaglandin F2α) is a synthetic analogue of PGF2α with oxytocic properties, commonly used to restore uterine tone.

AGN-191129, also known as Prostaglandin F2α alcohol methyl ether (PGF2α-OMe), is an analog of PGF2α in which the C-1 carboxyl group has been replaced by an O-methyl ether. The compound is reported to retain ocular hypotensive properties, but the receptors

Prostaglandin F2α 1,11-lactone (PGF2α 1,11-lactone) is a lipid-soluble prodrug of Prostaglandin F2α and can be used in studies about treating glaucoma. Prostaglandin F2α 1,11-lactone is active as an antifertility agent with greatly reduced vasoactivity.

15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.

Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.

Prostaglandin F2a-BSA is a hapten-carrier protein conjugate formed by coupling Prostaglandin F2a to bovine serum albumin (BSA). As a hapten, Prostaglandin F2a alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity. Prostaglandin F2a-BSA may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M PBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

Pgf2alpha 15-methyl ether is primarily used for the prevention of postpartum hemorrhage.

AL-3138 is a prostaglandin F2alpha (PGF2alpha) analogue which antagonizes FP prostanoid receptor-mediated inositol phosphates generation.

Bimatoprost isopropyl ester is an F-series prostaglandin analog, which has been approved as a hypotensive drug.

13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is an analog of PGF2α lacking unsaturation in the lower side chain. It induces luteolysis in hamsters with a potency five times greater than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 µg/100 g.[1]