panic

Reboxetine mesylate (FCE20124 mesylate) is a norepinephrine reuptake inhibitor with a Ki of 8.2 nM.

(±)-Paniculidine A, a natural product, is present in Murraya paniculata [1].

Andrographis paniculata extract contains active constituents such as flavonoids, polyphenols, and diterpene lactones, including andrographolide, dehydroandrographolide, and neoandrographolide. These compounds are renowned for their anti-inflammatory, antioxidant, immune-boosting, antiviral, and antibacterial properties.

Paniculoside II is a natural product from Stevia rebaudiana.

Paniculidine A is a natural product from Murraya exotica L.

Paniculidine B is a natural product of Murraya, Rutaceae. The catalog number is TN4736 and the CAS number is 97399-94-5. Paniculidine B can be used as a reference standard.

Paniculidine C is a natural product of Murraya, Rutaceae. The catalog number is TN4737 and the CAS number is 97399-95-6. Paniculidine C can be used as a reference standard.

Paniculoside I(FS-8855) is an iridoid glucoside from Pseudocaryopteris paniculata（CB Clarke）PD Cantino.

Paniculoside III is a natural product from the metabolites of the algicolous fungus Stevia paniculata.

PA Nic is a coumarin-caged nicotine. Releases nicotine when exposed to 390 ± 10 nm wavelength light (λmax = 404 nm). Suitable for two-photon uncaging at <900 nm (Maximum two-photon cross-section at 810 nm). Extinction coefficient (ε) 17,400 M-1cm-1. Evokes nicotinic currents in mouse brain slices under one and two-photon activation conditions.

PA-Nic TFA is a photoreactive nicotine compound that releases nicotine efficiently when subjected to photolysis by a laser at approximately 405 nm.

Skullcapflavone I (Standard) is a reference standard for research and analysis in studies involving Skullcapflavone I. Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. Skullcapflavone I selectively induces apoptosis in T-HSC/Cl-6 cells via caspase-3 and caspase-9 activation.

Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.

Sulcatone (6-Methyl-5-hepten-2-one) is an alarm/panic pheromone produce by ant species.

Tebideutorexant is a selective antagonist of the orexin-1 receptor and has demonstrated anti-panic effects in both rodent and human models of panic-anxiety. Tebideutorexant provides valuable insights into orexin signaling pathways in stress response and has potential utility as a tool compound for psychiatric and neurobehavioral disorder research.

Org-12962 is an effective and selective 5-HT2C receptor agonist pEC50: 7.01). Org-12962 shows antiaversive effects in a rat model of panic-like anxiety. Org-12962 also shows high effacy for the 5-HT2A and 5-HT2B receptors (pEC50s: 6.38 and 6.28, respectively).

Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of suicide in those over the age of 65. It is similar to Imipramine in that selective inhibition of the serotonin uptake in the brain.

Reboxetine (Norebox) is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sold under trade names including Edronax, Norebox, Prolift, Solvex, Davedax or Vestra. Reboxetine has two chiral centers, but it only exists as two enantiomers, (R, R)-(-)- and (S, S)-(+)-reboxetine.

BTG-1640 is used potentially for the treatment of anxiety and panic disorder.

Nefazodone hydrochloride (Serzone) is a serotoninergic modulating antidepressant that is used in therapy of depression, aggressive behavior and panic disorder.

Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor.[2] It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic

Fluvoxamine acid is a medication which functions as a selective serotonin reuptake inhibitor (SSRI) and σ1 receptor agonist. Fluvoxamine is used primarily for the treatment of obsessive-compulsive disorder (OCD), and is also used to treat major depressive disorder (MDD), and anxiety disorders such as panic disorder and post-traumatic stress disorder (PTSD).

Sertraline Free Base is a Selective Serotonin Reuptake Inhibitor (SSRI). It can treat depression, obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), social anxiety disorder, and panic disorder.

Fluoxetine oxalate is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.