p-4010

P-4010 is effective against herpes simplex.

Laromustine (VNP40101M) is a sulfonyl hydrolytic alkylating prodrug used in cancer therapy with significant anticancer activity. Inhibiting thioredoxin reductase can be used to study acute myeloid leukemia.

9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

MG1 peptide is a targeting peptide for M1 microglial cells. It can be conjugated with nanoparticles to traverse the blood-brain barrier, accurately identify M1 microglial cells, and enable controlled drug release and specific accumulation through an intelligent molecular switch. MG1 peptide is applicable in drug delivery research for ischemic stroke.