oxadiazole — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4604	HC-056456	HC 056456,3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide	Others
	HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) is a CatSper channel modulator.		Others
T60038	5-(5-methyl-1H-1,2,4-triazol-3-yl)-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole		Others
	5-(5-methyl-1H-1,2,4-triazol-3-yl)-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole can be used in the synthesis of heterocyclic compounds to inhibit HIF pathway activity.		Others
T9858	5-(3-bromo-4,5-dihydroisoxazol-5-yl)-3-(4-(tert-butyl)phenyl)-1,2,4-oxadiazole		Parasite
	Antileishmanial agent-2 is a 3-Br-isoxazoline-Based Inhibitors against Plasmodium falciparum (D10 and W2 strains) and Leishmania spp. (L. infantum and L. tropica) Promastigotes with IC50s of 0.035, 0.058, 3.5 and 7.5 μM.		Parasite
T13928	Tioxazafen		Others , Parasite
	Tioxazafen is a disubstituted oxadiazole, and is a broad-spectrum seed treatment nematicide.		Others , Parasite
T67321	2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole
	2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole is a useful organic compound for research related to life sciences. The catalog number is T67321 and the CAS number is 15420-02-7.
T66967	Ethyl 5-(4-bromophenyl)-1,3,4-oxadiazole-2-carboxylate
	Ethyl 5-(4-bromophenyl)-1,3,4-oxadiazole-2-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66967 and the CAS number is 931760-32-6.
T66233	2-([1,1-Biphenyl]-4-yl)-5-phenyl-1,3,4-oxadiazole
	2-([1,1-Biphenyl]-4-yl)-5-phenyl-1,3,4-oxadiazole is a useful organic compound for research related to life sciences. The catalog number is T66233 and the CAS number is 852-38-0.
T33685	Nitrobenzoxadiazolealanine
	Nitrobenzoxadiazolealanine is a fluorescent dinitrophenyl analog.
T37002	7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (ammonium salt)
	7-Fluoro-2,1,3-benzoxadiazole-4-sulfonate (SBD-F) is a thiol-reactive fluorogenic probe.1It has been used to quantify the levels of homocysteine, cysteine, and cysteamine in human plasma.2SBD-F displays excitation/emissi...
T60487	DDO-7263		Nrf2
	DDO-7263 is a 1,2,4-Oxadiazole derivative that upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 is a potent Nrf2 activator th...		Nrf2
T35108	Way 120744	Way120744,Way-120744
	Way 120744 is a new naphthyl 3h -1,2,3,5-oxadiazole 2-oxide.
T35887	MBD
	MBD, a novel fluorescent probe (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), is utilized to study the conformation of protein and nucleoprotein. Its application is extended to bacterial ribosomes, as well as b...
T12793	(S)-BI 665915		Others
	(S)-BI 665915 is an orally active inhibitor of oxadiazole-containing 5-lipoxygenase-activating protein (FLAP)(IC50 of 1.7 nM for FLAP binding)..		Others
T37465	CAY10742
	CAY10742 is an orally bioavailable oxadiazole antibiotic.1It is active against the Gram-positive bacteriaS. aureus,S. epidermidis,S. haemolyticus,B. cereus,B. licheniformis,E. faecalis, andE. faecium(MICs = 1-4 μg/ml), i...
T71882	Pifexole
	Pifexole is the 1,2,4-oxadiazole derivative. It has a similar profile of muscle-relaxant activity in animals to that of chlorzoxazone. In rats, pifexole is reported to be seven times more potent than chlorzoxazone in inh...
T63027	Antibacterial agent 66
	Antibacterial agent 66 (Compound 6q) is a trifluoromethylpyridine 1,3,4-oxadiazole derivative active against Xanthomonas oryzae pv. oryzae (Xoo) (EC50: 7.2 μg/mL).
T80925	Tuberculosis inhibitor 12
	Tuberculosis Inhibitor 12, an oxadiazole derivative, effectively inhibits Mycobacterium tuberculosis, demonstrating inhibition rates of 82% and 78% at a concentration of 20 μM on 7H9-Tw-OADC media, respectively [1].
T81487	Phidianidine B
	Phidianidine B, a natural product with pronounced cytotoxic properties, is a 1,2,4-oxadiazole marine metabolite extractable from a marine mollusk [1].
T79353	P-gp/BCRP-IN-2
	P-gp/BCRP-IN-2 (compound 15), an oxadiazole derivative, functions as a dual inhibitor targeting both the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRP (IC50: 600 nM). Additionally, it bolsters the anti-prolifera...
T37832	CAY10761	CAY10761
	CAY10761 is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50s = 467 and 429 μM for the human and snake venom enzymes, respectively).1,2 It also inhibits mushroom tyrosinase (Ki = 1.9 μM) an...