ossification

LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors; possesses differences towards ALK2(IC50=1.3 nM) versus ALK1 3 compared to other inhibitors.

Secalciferol is a Vitamin D metabolite,Secalciferol is a possibly anti-inflammatory steroid which is involved in bone ossification.

SR11237 is a Pan retinoid X receptor (RXR) agonist. SR11237 causes RXR RXR homodimers to form and transactivate a reporter gene containing a RXR-response element.

The compound AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG facilitates bone ossification and has potential applications in the study of conditions associated with osteogenic insufficiency or diminished bone mineral density (BMD), including osteoporosis [1].

Zilurgisertib fumarate (INB-000928 fumarate, NBU-928 fumarate), a selective ALK-2 inhibitor, is in development for the treatment of ectopic ossification and progressive fibrodysplasia ossificans.