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By Target- Lipoxygenase
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Results for "
nnk
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Disease Modeling1
NNK
Nicotine-derived nitrosamine ketone
T2053364091-91-4
NNK is a nitrosated derivative of nicotine that activates the ERK1/2 and PKCα signaling pathways, induces Bcl2 phosphorylation at Ser70, and activates c-Myc at Thr58 and Ser62, thereby promoting the proliferation and survival of human lung cancer cells, and is commonly used to establish lung cancer mouse models.
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