nicotinate

NAAD sodium salt (NAAD Na salt) is a substrate of nicotinamide adenine dinucleotide synthase and can be used in studies about the specificity and kinetics of the substrate.

Tocopherol nicotinate is an antioxidant. It is used for skin conditioning.

Brefeldin A 4-O-nicotinate (CHNQD-01228) is a dual inhibitor of Arf1 and BMX proteins with an IC50 value of 0.22 μM for T24 cell proliferation. It also suppresses T24 cell migration and colony formation in a dose-dependent manner, induces G1 phase arrest, and triggers apoptosis. By targeting BMX proteins, it inhibits the AKT/p-AKT and STAT3/p-STAT3 signaling pathways, while also inhibiting Arf1 proteins to eliminate bladder cancer stem cells and activate antitumor immunity, thus exhibiting anticancer activity. Brefeldin A 4-O-nicotinate is applicable in research related to bladder cancer.

Chromium nicotinate is a niacin salt of trivalent chromium, used as a supplement for type 2 diabetes.

Ascorbyl nicotinate is a bioactive chemical.

(±)-α-Tocopherol nicotinate is a useful organic compound for research related to life sciences. The catalog number is T64563 and the CAS number is 51898-34-1.

Norfloxacin (nicotinate) is a useful organic compound for research related to life sciences. The catalog number is T66435 and the CAS number is 118803-81-9.

CHS-828 nicotinate is a CHS-828 salt with Nicotinic acid.. CHS-828 also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting the nuclear factor-kappaB translocation but unlikely through down-regulation of proteasome. CHS 828 has shown promising anticancer activity in experimental tumor models and primary cultures of cancer cells from patients. CHS 828 showed a synergistic effect with melphalan in 67%, doxorubicin in 47%, etoposide in 38% and Ara-C in 14% of AML samples.

Methyl nicotinate-D4 is the deuterated form of Methyl nicotinate (T5562). This compound, a methyl ester found in alcoholic beverages, is utilized as an active ingredient in over-the-counter topical preparations for studying muscle and joint pain.

Ethyl nicotinate ,with CAS No. 614-18-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Ethyl nicotinate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Myristyl nicotinate (Tetradecyl nicotinate) is an ester prodrug being developed for delivering nicotinic acid (NIC) into the skin to prevent actinic keratosis and its progression to skin cancer.

Hexyl nicotinate (AI3 15769) is a cutaneous vasodilator and can be used in research on non-immunologic contact urticaria on the scalp, face, and back.

Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increased energy.

Inositol nicotinate (Mesotal) has the effect of lowering cholesterol and expanding peripheral blood vessels for hypercholesterolemia and atherosclerosis.

Methyl nicotinate (methyl pyridine-3-carboxylate) is the methyl ester of that is used as an active ingredient as a rubefacient in over-the-counter topical preparations indicated for muscle and joint pain. The action of methyl nicotinate as a rubefacient is thought to involve peripheral vasodilation.

Benzyl nicotinate (Pycaril) is a agonist of GPR109A receptor and GPR109B receptor

Methyl 4-(trifluoromethyl)nicotinate ,with CAS No. 175204-82-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Methyl 4-(trifluoromethyl)nicotinate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Phenyl nicotinate is a biochemical.

Nicodan Percutan (Propylnicotinat) is the propyl ester form of niacin, which is found in various animal and plant tissues to form the coenzymes NAD and NADP.

Methyl 6-chloronicotinate ,with CAS No. 73781-91-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Methyl 6-chloronicotinate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Ethyl 2-chloronicotinate ,with CAS No. 1452-94-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Ethyl 2-chloronicotinate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Methyl 2,6-dichloroisonicotinate ,with CAS No. 42521-09-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Methyl 2,6-dichloroisonicotinate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Methyl 6-methylnicotinate ,with CAS No. 5470-70-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Methyl 6-methylnicotinate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Ethyl 2-cyanonicotinate, with CAS No. 75358-90-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Ethyl 2-cyanonicotinate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.