naproxen

Naproxen ((S)-Naproxen) is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities.

(R)-Naproxen, an anti-inflammatory agent, has antipyretic and analgesic properties. Both the acid and its sodium salt are used in the therapy of acute gout or dysmenorrhea, musculoskeletal disorders, rheumatoid arthritis and other rheumatic.

Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.

Naproxen is a COX-1 and COX-2 inhibitor (IC50s: 8.72 and 5.15 μM, respectively in cell assay). Naproxen etemesil is a lipophilic and non-acidic prodrug of naproxen. It is hydrolyzed to pharmacologically active Naproxen once absorbed.

Racemic Naproxen is a biochemical substance.

Naproxen glucuronide is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a nonselective COX inhibitor.

Naproxen ethyl ester is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a non-selective COX inhibitor.

(S)-O-Desmethyl naproxen, a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (+)-naproxen ((S)-naproxen), is produced through the action of cytochrome P450 (CYP) isoforms CYP1A2 and CYP2C9.

Naproxen methyl ester is a prodrug and ester derivative of Naproxen. It shows potential for research in arthritis and other inflammatory diseases.

(R)-Naproxen acyl-β-D-glucuronide ((R)-Naproxen-β-D-glucuronide) is a metabolite with anti-inflammatory properties. It serves as a sensitive fluorescent substrate for pre-glutamyl peptidase 1, producing a blue reaction upon cleavage.

Naproxen (Standard) is the standard substance of Naproxen, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Naproxen ((S)-Naproxen) is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities.

(±)-Naproxen-D3 (Standard) is a reference standard of (±)-Naproxen-D3 intended for quantitative analysis, quality control, and related biochemical research applications.

Naproxen-[13C,D3], Racemic Mixture (Standard) is a reference standard of Naproxen-[13C,D3], Racemic Mixture intended for quantitative analysis, quality control, and related biochemical research applications.

(±)-Naproxen-D3 (Alpha-Methyl-D3) (Standard) is a reference standard of (±)-Naproxen-D3 (Alpha-Methyl-D3) intended for quantitative analysis, quality control, and related biochemical research applications.

6-Methoxy-2-naphthoic acid (6-Methoxy-2-naphthalenecarboxylic acid) is an modulator of NMDAR.

Naproxcinod is a derivative of naproxen exhibiting analgesic and anti-inflammatory activity. As a cyclooxygenase (COX)-inhibitory nitric oxide donor (CINOD), it is indicated for osteoarthritis and inflammatory conditions.

α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)

Cinaproxen is a derivative of naproxen, utilized for the prevention and treatment of oxidative stress.

Pregabalin naproxencarbil (Pregabalinum naproxencarbilum) is a gamma-aminobutyric acid (GABA) mimic with analgesic properties.

2-Acetyl-6-methoxynaphthalene, the key intermediate of naphthalene tome and naproxen, is used in synthetic non-steroidal anti-inflammatory analgesic medicine and.

4-Butoxyphenol (P-Butoxyphenol) is a phenolic compound with a wide range of applications in science and industry. It is often used in the synthesis of other compounds such as 4-butoxyphenylacetic acid and 4-butoxyphenylacetonitrile. It is also used in the synthesis of drugs such as ibuprofen and naproxen.

Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.

Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention[1][2]. [1]. Furugohri T, et al. DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles. J Thromb Haemost. 2008 Sep;6(9):1542-9.[2]. Mendell J, Lee F, Chen S, The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor. J Cardiovasc Pharmacol. 2013 Apr 23.

1,3-Distearoyl glycerol, a diacylglycerol with stearic acid at the sn-1 and sn-3 positions, is present in wheat bran extract. It is utilized in creating prodrug versions of NSAIDs (ibuprofen, naproxen, and diclofenac) with decreased ulcerogenicity.