mosapride

Mosapride (AS-4370) is a selective 5HT4 agonist

Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.

Mosapride Citrate is a 5-HT4 receptor agonist used to stimulate gastrointestinal motility via acetylcholine. Mosapride Citrate facilitates acetylcholine release from the enteric cholinergic neurons.

Des-4-fluorobenzyl Mosapride, the main metabolite of mosapride, acts as a gastroprokinetic agent improving upper gastrointestinal (GI) motility by stimulating the serotonin receptor 4 (5-HT4; EC50= 74.2 nM, in guinea pig ileal longitudinal muscle myenteric plexus). It has been shown to increase colonic motility in dogs, horses, and guinea pigs in vivo. Mosapride, including this metabolite, is utilized in human and veterinary medicine to mitigate post-surgical and Parkinson's-induced constipation.

Mosapride N-Oxide, a major active metabolite of Mosapride, is a gastroprokinetic agent that acts as a selective 5HT4 agonist.

Mosapride-d5 is a deuterated compound of Mosapride. Mosapride has a CAS number of 112885-41-3. Mosapride is a selective 5HT4 agonist

Des-4-Fluorobenzyl Mosapride-d5 is a deuterated compound of Des-4-Fluorobenzyl Mosapride. Des-4-Fluorobenzyl Mosapride has a CAS number of 152013-26-8.