l-fucose

GDP-β-L-fucose is a metabolite in plant and animal. It used for microbe agglutination assay and agglutination inhibition assay. GDP-β-L-fucose is formed by the oxidation-reduction and epimerization of GDP-R-D-mannose in most organisms.

2F-Peracetyl-Fucose (1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucopyranos) is a potent fucosyltransferase (FUT) inhibitor that suppresses salivary acidification and fucosylation in an in vitro inflammatory model.

2-Deoxy-2-fluoro-L-fucose is a fucosylation inhibitor that inhibits the de novo synthesis of GDP-fucose in mammalian cells, effectively inhibits the proliferation of human cancer and primary endothelial cells, and has potential as an angiogenic therapeutic agent. It also inhibits fucosylation of plant cell wall polysaccharides, particularly affecting the dimerization of the pectin-like polysaccharide RG-II, thereby inhibiting root growth and cell elongation.2-Deoxy-2-fluoro-L-fucose also reduces the phosphorylation of Smad 1/5 and Smad 2 in 4T1 cells.

GDP-L-fucose is a nucleotide sugar widely found in fungi and plants, playing a role in both the slave and secondary remedial metabolic pathways.

GDP-L-fucose disodium, a nucleotide sugar, serves as a crucial substrate for fucose oligosaccharides biosynthesis by providing the fucose moiety. Its formation follows two metabolic pathways: the primary de novo pathway and the secondary remedial pathway [1].

6-Alkynyl-fucose, a widely used fucosylation probe, acts by strongly inhibiting fucosylation and GDP-fucose synthetase FX and halting hepatoma invasion.

1.(-)-Fucose (6-Desoxygalactose) can anti-infective, anti-cancer, enhance immunity 2. (-)-Fucose is a skin moisturizing and delaying skin aging 3. (-)-Fucose is a nutritional supplement

Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.

α-L-fucopyranose, an endogenous metabolite and six-carbon deoxyhexose, is present at the terminal or anterior position of many cell surface oligosaccharide ligands, mediates cell recognition and adhesion signaling pathways, and is a potentially critical molecule in pathological processes, including tumors.

D-(+)-Fucose is a non-metabolizable analog of l-arabinose and an inducer of β-methylgalactoside permease. It inhibits the induction of the l-arabinose manipulator and blocks the growth of Escherichia coli B/r on mineral salts medium with l-arabinose.

GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM).GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of

Alpha-1,3/4-Fucosyltransferase (α1,3/4FucT) (Hp3/4FT) is found in Helicobacter pylori and catalyzes the transfer of fucose from donor GDP-beta-l-fucose to the GlcNAc [1].

Lactodifucotetraose (Difucosyllactose), a tetrasaccharide extracted from human milk, consists of one D-glucose, one D-galactose, and two L-fucose molecules [1].

Ulex Europaeus Agglutinin I (peroxidase) (UEA I (peroxidase)) exhibits specificity for the H blood group antigen and has an affinity for L-fucose.

Fucosyltransferase 11 (EC:2.4.1.-, FUT11) attaches α-L-fucose to glycoprotein substrates, specifically on asialoglycoprotein glycans and biantennary N-glycan acceptors. This enzyme is significant in the field of oncology.