japonica

Emodin 6-O-β-D-glucoside (Glucoemodin) can protect barrier integrity and inhibit HMGB1-mediated inflammatory responses, which suggests a potential use as a therapy for sepsis or septic shock. Emodin 6-O-beta-D-glucoside has anti-inflammatory activities and also may have significant therapeutic benefits against diabetic complications and atherosclerosis.

Bijaponicaxanthone C is a useful organic compound for research related to life sciences and the catalog number is T124040.

Troxerutin (Trihydroxyethylrutin), a natural bioflavonoid, is isolated from Sophora japonica. It has many benefits and medicinal properties.

1. Chelidonine (Stylophorin) isolated from Chelidonium majus efficiently induced apoptosis in HeLa cells through possible alteration of p38-p53 and AKT PI3 kinase signalling pathways. 2. Chelidonine is a promising model compound for overcoming MDR and for enhancing cytotoxicity of chemotherapeutics, especially against leukaemia cells, its efficacy needs to be confirmed in animal models. 3. Chelidonine may be a potential therapeutic agent against metastasis of invasive human cancer cells, exhibits antimigratory and antiinvasive effects in MDA-MB-231 cells, by suppressing COL-induced integrin signaling, through inhibiting the formation of the IPP complex and subsequent downregulation of IPP downstream signaling molecules, such as Akt and ERK1 2.

(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium floribundum. It potently inhibits osteoclastogenesis and facilitates bone healing and increased bone mass through osteoblast differentiation, mediated by the estrogen receptor (ER) β.

Butylchlorogenate is a natural compound isolated from Lonicera japonica, Urceola rosea.

3'- O- Acetylhamaudol, isolated from the roots of Angelica japonica, exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation.

2,3,4,5-Tetracaffeoyl-D-Glucaric acid is a compound isolated from Inula japonica that inhibits fat accumulation and reduces body fat and can be used in the study of obesity.

Rabdosin A is a diterpenoid antitumor constituent from Rabdosia japonica.

Asebotoxin III is a diterpenoid obtained from the leaves of Asebi, Pieris japonica.

Secoxyloganin possesses a hepato-protective effect. Secoxyloganin possesses antibacterial activity. Secoxyloganin has cytotoxic activity against UACC-62 cell line.Secoxyloganin possesses the perfect protective effect on PRRSV infected cell and with the minimum protection concentration of 6. 25 μg mL.

Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxiolytic and sedative-hypnotic drug in folk medicine.

1. Sweroside possesses strong hepatoprotective effect. 2. Sweroside is a promising osteoporosis therapeutic natural product, has anti-osteoporotic effect on the human MG-63 cells and rat osteoblasts.

(6E,12E)-Tetradecadiene-8,10-diyne-1,3-diol is an antibacterial compound isolated from the roots of Atractylodes japonica, exhibiting anti-methicillin-resistant Staphylococcus aureus (MRSA) activity with MIC values of 4-32 μg mL, and can be used for the research of bacterial infection [1].

N-Butyl α-D-fructofuranoside, extracted from the root barks of Ulmus davidiana var. japonica, amplifies Nrf2 activity via JNK activation and exhibits anti-inflammatory properties [1] [2].

Polygalasaponin LII, a triterpenoid saponin, can be isolated from the roots of Polygala japonica Houtt [1].

Glaucocalyxin D, an ent-kauranoid-type diterpenoid extracted from Rabdosia japonica, exhibits cytotoxic properties against a range of human tumor cell lines, making it a valuable compound for cancer research [1].

3-Acetyl-11-keto-ursolic acid (Compound 18), a triterpenoid derived from Eriobotrya japonica leaves, exhibits inhibitory activity against 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) and holds potential for anti-diabetes research [1].

Protostemotinine is a natural product from Stemona japonica.

Bayogenin 3-O-beta-D-glucopyranoside is a natural product from Polygala japonica Houtt.

Epivogeloside is a product from Lonicera japonica.

(-)-Pinoresinol is isolated from the whole plant of Serissa japonica (Thunb.) Thunb.

Sophorabioside is a natural product from Sophora japonica.

3-Hydroxymandelic Acid is a metabolite of Phenylephrine. 3-Hydroxymandelic Acid is a metabolite of Phenylephrine, which is an α-receptor agonist.