is-401

Diisopropylamine dichloroacetate stimulates smooth muscle & strongly inhibits acetylcholinesterase activity.

Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits FGFR4, leading to the inhibition of tumor cell proliferation in FGFR4-overexpressing cells. It is a receptor tyrosine kinase upregulated in certain tumor cells and involved in proliferation, differentiation, angiogenesis, and survival.

Diltiazem (CRD 401 free base) is an orally available L-type Ca2+ channel blocker with antihypertensive, antiarrhythmic, and cardioprotective properties that prevent post-reperfusion myocardial injury, angina pectoris, and cardiovascular-related diseases.

CORM-401 is an oxidant-sensitive CO-releasing molecule used in the research of oxidative stress-mediated pathologies and inflammation [inflammatory].

WQ-C-401 is an orally active inhibitor of the platelet-derived growth factor receptor (PDGFR). It inhibits cell proliferation by blocking PDGFR auto-phosphorylation in a concentration-dependent manner, with EC50 values of 3.5 nM for PDGFRαY849 and 5.8 nM for PDGFRβY1021. Additionally, WQ-C-401 suppresses the proliferation and migration of PASMCs by inhibiting PDGF-BB-induced phosphorylation of ERK1 2, reduces collagen I synthesis, and increases α-SMA expression, thereby preventing pulmonary vascular remodeling. This compound shows promise for research in the field of pulmonary arterial hypertension.

Casein kinase1δ-IN-13 (compound 401) is an inhibitor of Casein kinase1δ. It is utilized in the research of neurodegenerative diseases.

CC-401 is a specific inhibitor of JNK (Ki: 25-50nM).

JX 401 is a p38α inhibitor.

MM-401 is a specific inhibitor of histone H3K4 methyltransferase MLL1 activity that acts by reprogramming mouse epiblast stem cells to naive pluripotency.

Ethoheptazine Citrate, also known as Zactane and WY-401, is a mycolic acid synthesis inhibitor used to treat tuberculosis.

Olodanrigan sodium (EMA-401 sodium) is an orally active and selective angiotensin II type 2 receptor (AT2R) antagonist, which can be used in research on neurological diseases.

CH 401-Na is a bio-active chemical.

Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets mTOR but not PI3K.

LEI-401 is a selective and potent NAPE-PLD inhibitor that crosses the blood-brain barrier (IC50: 27 nM).LEI-401 reduces the level of n-acylethanolamines (NAEs) in the brain of free-ranging mice and modulates their emotional behaviour.

CC-401 Hydrochloride (CC401 HCl) is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor (Ki of 25 to 50 nM.)with potential antineoplastic activity.

FK-401 is an inhibitor of chymotrypsin.

TCS-401 is an insulin receptor sensitizing agent; Selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B).

TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) with a Ki value of 0.29 μM.

Peptide 401 is an antimicrobial peptide (AMP) derived from the venom of bees and wasps. Peptide 401 induces mast cell degranulation, activating histamine release from peritoneal mast cells. Additionally, peptide 401 exhibits some anti-inflammatory activit

Poloxamer 401 L121 is a block copolymer composed of polyoxyethylene and polyoxypropylene. It is utilized in nanoparticle engineering as a lymphocyte nutrition particle, an inhibitor of multidrug resistance and adjuvant activity, or in the cosmetics industry as a surfactant and emulsifier.