is-401

Diisopropylamine dichloroacetate stimulates smooth muscle & strongly inhibits acetylcholinesterase activity.

Compound Fr13881, with CAS No. 401-73-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13881 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Diltiazem (CRD 401 free base) is an orally available L-type Ca2+ channel blocker with antihypertensive, antiarrhythmic, and cardioprotective properties that prevent post-reperfusion myocardial injury, angina pectoris, and cardiovascular-related diseases.

CORM-401 is an oxidant-sensitive CO-releasing molecule used in the research of oxidative stress-mediated pathologies and inflammation [inflammatory].

Casein kinase1δ-IN-13 (compound 401) is an inhibitor of Casein kinase1δ. It is utilized in the research of neurodegenerative diseases.

BSI-401 is an oral inhibitor of PARP-1. It can inhibit pancreatic cancer either when used alone or in synergy with Oxaliplatin.

Zandelisib (ME-401) hydrochloride is a selective, orally active, non-covalent PI3Kδ inhibitor. It effectively and persistently inhibits AKT phosphorylation and downstream signaling pathways. Zandelisib hydrochloride is utilized in research on malignant tumors such as relapsed/refractory B-cell lymphoma.

CRBN ligand-401 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit cereblon protein. It can be coupled with a target protein ligand via a linker to form a PROTAC.

CC-401 is a specific inhibitor of JNK (Ki: 25-50nM).

JX 401 is a p38α inhibitor.

MM-401 is a specific inhibitor of histone H3K4 methyltransferase MLL1 activity that acts by reprogramming mouse epiblast stem cells to naive pluripotency.

Ethoheptazine Citrate, also known as Zactane and WY-401, is a mycolic acid synthesis inhibitor used to treat tuberculosis.

Olodanrigan sodium (EMA-401 sodium) is an orally active and selective angiotensin II type 2 receptor (AT2R) antagonist, which can be used in research on neurological diseases.

CH 401-Na is a bio-active chemical.

Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) is a synthetic DNA-PK inhibitor (IC50 = 0.28 μM) that also targets mTOR but not PI3K.

LEI-401 is a selective and potent NAPE-PLD inhibitor that crosses the blood-brain barrier (IC50: 27 nM).LEI-401 reduces the level of n-acylethanolamines (NAEs) in the brain of free-ranging mice and modulates their emotional behaviour.

Roblitinib (FGF-401) is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) with potential antineoplastic activity. Upon administration, Roblitinib binds to and inhibits FGFR4, leading to the inhibition of tumor cell proliferation in FGFR4-overexpressing cells. It is a receptor tyrosine kinase upregulated in certain tumor cells and involved in proliferation, differentiation, angiogenesis, and survival.

CC-401 Hydrochloride (CC401 HCl) is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor (Ki of 25 to 50 nM.)with potential antineoplastic activity.

FK-401 is an inhibitor of chymotrypsin.

TCS-401 is an insulin receptor sensitizing agent; Selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B).

TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) with a Ki value of 0.29 μM.

Anti-FOLH1/PSMA Antibody (J591) (MEDI3726 antibody; ADCT-401 antibody) is a humanized monoclonal antibody (mAb) that specifically targets PSMA. This antibody is utilized in prostate cancer research.

GBR-401 is a humanized anti-CD19 monoclonal antibody with high affinity for FcγRIIIa. It exhibits potent cytotoxicity in vitro and in vivo against various B-cell malignancies. GBR-401 induces cell death through antibody-dependent cellular cytotoxicity (ADCC) and direct cytotoxic effects. In severe combined immunodeficiency (SCID) mouse models with various xenografts, GBR-401 effectively eliminates malignant B cells and prolongs survival.

Peptide 401 is an antimicrobial peptide (AMP) derived from the venom of bees and wasps. Peptide 401 induces mast cell degranulation, activating histamine release from peritoneal mast cells. Additionally, peptide 401 exhibits some anti-inflammatory activit