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By Target- IRE1
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Results for "
ire1α kinase in 1
" in TargetMol Product Catalog- Inhibitors & Agonists9
IRE1α kinase-IN-4
T635112771006-45-0
IRE1α kinase-IN-4 (compound 6) is a potent IRE1α inhibitor with a Ki value of 140 nM, functioning as an ATP-competitive ligand for IRE1α [1].
- $1,520
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QTY
IRE1α kinase-IN-8
T790621338933-29-1
IRE1α kinase-IN-8, a benzoheterocyclecarboxaldehyde derivative, is a potent inhibitor of IRE-1α used in research on diseases related to the unfolded protein response and regulated IRE1-dependent decay (RIDD) [1].
- $1,520
Size
QTY
IRE1α kinase-IN-9
T790631338933-30-4
IRE1α kinase-IN-9 (compound 2) is a potent inhibitor of IRE-1α with an average IC50 value of less than 0.1 μM, and it is suitable for research into diseases related to the unfolded protein response or regulated IRE1-dependent decay (RIDD) [1].
- $1,520
Size
QTY
IRE1α kinase-IN-1
T95642328097-41-0
IRE1α kinase-IN-1 is a highly selective IRE1α (ERN1) inhibitor, with an IC50 of 77 nM, displaying 100-fold selectivity over the IRE1β isoform. It inhibits ER stress-induced IRE1α oligomerization and autophosphorylation, as well as IRE1α RNase activity (IC50=80 nM).
- $118
Size
QTY
IRE1α kinase-IN-2
IRE1α kinase-IN-2
T388411414938-21-8
IRE1α kinase-IN-2 is a highly potent inhibitor of IRE1α kinase, demonstrating an EC50 of 0.82 μM and impeding IRE1α kinase autophosphorylation with an IC50 of 3.12 μM. It also effectively inhibits the splicing of XBP1 mRNA in wild-type cell lines.
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IRE1α kinase-IN-6
IRE1α kinase-IN-6
T403362715123-88-7
IRE1α kinase-IN-6 is a potent IRE1α inhibitor with an IC50 value of 4.4 nM.
- $970
Size
QTY
IRE1α kinase-IN-5
T63734
IRE1α kinase-IN-5 (compound 7) is a potent ATP-competitive inhibitor of IRE1α with a Ki value of 98 nM.
- $1,520
Size
QTY
IRE1α kinase-IN-3
T638392416223-41-9
IRE1α kinase-IN-3 is a potent, ATP-competitive inhibitor of IRE1α (Ki: 480 nM).
- $1,520
Size
QTY
IRE1α kinase-IN-7
T726411414938-22-9
IRE1α kinase-IN-7 is a chemical compound functioning as an inhibitor of IRE1α kinase, primarily utilized in the research of diseases related to endoplasmic reticulum stress.
- $1,670
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